A review on recent insights on cardiovascular diseases drug design using natural products and in silico studies
Cardiovascular diseases (CVDs), which are among the leading causes of morbidity and mortality, are strongly associated with unhealthy eating habits. Compounds originating from plants, natural products, and balanced diets have been identified as potential remedies for CVDs. Natural products that impr...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-10-01
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| Series: | Kuwait Journal of Science |
| Subjects: | |
| Online Access: | https://www.sciencedirect.com/science/article/pii/S2307410825000823 |
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| Summary: | Cardiovascular diseases (CVDs), which are among the leading causes of morbidity and mortality, are strongly associated with unhealthy eating habits. Compounds originating from plants, natural products, and balanced diets have been identified as potential remedies for CVDs. Natural products that improve cardiovascular health may include fruits, vegetables, spices, herbs, propolis, honey, and red wine. This review focused on articles published from 2015 onwards from Scopus, Google Scholar, and Pubmed, highlighting key studies on natural products and in silico research for managing CVDs, including their biosynthesis, mode of action, and origins. Overall, this assessment indicated that in silico research and natural products have been useful in providing insightful cures for some CVDs, but they still have a lot of unrealized potential. Some of the target proteins and protein databank identification numbers that may be utilized in in silico research for cardiovascular disorders were displayed. |
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| ISSN: | 2307-4108 2307-4116 |