Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review

The coronavirus disease-2019 (COVID-19) infection was first detected at the end of December 2019. Encephalitis, ischemic stroke, ataxia, and peripheral nerve diseases were reported in patients after the COVID-19 infection. Guillain-Barré syndrome (GBS) and cranial nerve involvement are also frequent...

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Main Authors: Kadriye Guleda Keskin, Murat Fatih Pul, Ahmet Akpinar, Isil Kalyoncu Aslan, Eren Gozke
Format: Article
Language:English
Published: Galenos Publishing House 2023-06-01
Series:Haseki Tıp Bülteni
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Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/guillain-barr-syndrome-presenting-with-facial-dipl/60802
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author Kadriye Guleda Keskin
Murat Fatih Pul
Ahmet Akpinar
Isil Kalyoncu Aslan
Eren Gozke
author_facet Kadriye Guleda Keskin
Murat Fatih Pul
Ahmet Akpinar
Isil Kalyoncu Aslan
Eren Gozke
author_sort Kadriye Guleda Keskin
collection DOAJ
description The coronavirus disease-2019 (COVID-19) infection was first detected at the end of December 2019. Encephalitis, ischemic stroke, ataxia, and peripheral nerve diseases were reported in patients after the COVID-19 infection. Guillain-Barré syndrome (GBS) and cranial nerve involvement are also frequently observed. We report five patients with GBS after the COVID-19 infection. Four of them had facial diplegia. Electromyography of the three patients mentioned having acute motor and sensory axonal neuropathy, whereas two had demyelinating and mixed types. Mixed types were more frequent in studies, and a significant relationship was found with the demyelinating type. The high rate of facial diplegia in our cases suggests that more research should be conducted on the cranial nerve involvement in GBS patients with COVID-19 infection. Our aim was to focus on cranial nerve involvement in COVID-19 patients.
format Article
id doaj-art-530348e8d6ea4392b5955abcf5390f27
institution Kabale University
issn 1302-0072
2147-2688
language English
publishDate 2023-06-01
publisher Galenos Publishing House
record_format Article
series Haseki Tıp Bülteni
spelling doaj-art-530348e8d6ea4392b5955abcf5390f272025-08-20T03:36:34ZengGalenos Publishing HouseHaseki Tıp Bülteni1302-00722147-26882023-06-0161320620910.4274/haseki.galenos.2023.893813049054Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature ReviewKadriye Guleda Keskin0Murat Fatih Pul1Ahmet Akpinar2Isil Kalyoncu Aslan3Eren Gozke4 University of Health Sciences Turkey, Fatih Sultan Mehmet Training and Research Hospital, Clinic of Neurology, Istanbul, Turkey University of Health Sciences Turkey, Fatih Sultan Mehmet Training and Research Hospital, Clinic of Neurology, Istanbul, Turkey University of Health Sciences Turkey, Fatih Sultan Mehmet Training and Research Hospital, Clinic of Neurology, Istanbul, Turkey University of Health Sciences Turkey, Fatih Sultan Mehmet Training and Research Hospital, Clinic of Neurology, Istanbul, Turkey University of Health Sciences Turkey, Fatih Sultan Mehmet Training and Research Hospital, Clinic of Neurology, Istanbul, Turkey The coronavirus disease-2019 (COVID-19) infection was first detected at the end of December 2019. Encephalitis, ischemic stroke, ataxia, and peripheral nerve diseases were reported in patients after the COVID-19 infection. Guillain-Barré syndrome (GBS) and cranial nerve involvement are also frequently observed. We report five patients with GBS after the COVID-19 infection. Four of them had facial diplegia. Electromyography of the three patients mentioned having acute motor and sensory axonal neuropathy, whereas two had demyelinating and mixed types. Mixed types were more frequent in studies, and a significant relationship was found with the demyelinating type. The high rate of facial diplegia in our cases suggests that more research should be conducted on the cranial nerve involvement in GBS patients with COVID-19 infection. Our aim was to focus on cranial nerve involvement in COVID-19 patients. http://www.hasekidergisi.com/archives/archive-detail/article-preview/guillain-barr-syndrome-presenting-with-facial-dipl/60802 guillain-barré syndromefacial diplegiasars-cov-2
spellingShingle Kadriye Guleda Keskin
Murat Fatih Pul
Ahmet Akpinar
Isil Kalyoncu Aslan
Eren Gozke
Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
Haseki Tıp Bülteni
guillain-barré syndrome
facial diplegia
sars-cov-2
title Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
title_full Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
title_fullStr Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
title_full_unstemmed Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
title_short Guillain-Barré Syndrome Presenting with Facial Diplegia Due to SARS-CoV-2 Infection: A Case Series and Current Literature Review
title_sort guillain barre syndrome presenting with facial diplegia due to sars cov 2 infection a case series and current literature review
topic guillain-barré syndrome
facial diplegia
sars-cov-2
url http://www.hasekidergisi.com/archives/archive-detail/article-preview/guillain-barr-syndrome-presenting-with-facial-dipl/60802
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