Crystal structure of the fungal mannosyltransferase Och1 reveals active site primed for N-glycan binding.

The outermost layer of a fungi's cell wall serves as the organism's point of first contact with its environment, or host. Heavily glycosylated glycoproteins anchor a complex meshwork of branching mannose chains, forming the outer cell wall layer in most yeast and mold species. Outer mannan...

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Bibliographic Details
Main Authors: Emma T R Kelly, Dmitry Rodionov, Barry Sleno, Pedro A Romero, Albert M Berghuis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329259
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