PROGNOSTIC SIGNIFICANCE OF Ki67, CYCLOOXYGENASE-2 (COX-2) AND p16ink4a IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER

PROGNOSTIC SIGNIFICANCE OF Ki67, CYCLOOXYGENASE-2 (COX-2) AND p16ink4a IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER

The increased expression levels of Ki67, cyclooxygenase-2 (COX-2) and p16ink4a proteins after neoadjuvant chemotherapy for locally advanced cervical cancer were shown to correlate with unfavorable prognosis. The level of Ki67 expression before treatment was 85 % in patients, who subsequently develop...

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Bibliographic Details
Main Authors: O. N. Churuksaeva, L. A. Kolomiets, O. V. Savenkova, V. V. Nedosekov, M. K. Ibragimova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2016-11-01
Series:Сибирский онкологический журнал
Subjects:
locally advanced cervical cancer
ki67
cox-2
p16ink4a
prognostic factors
Online Access:https://www.siboncoj.ru/jour/article/view/402
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