Deferiprone protects against photoreceptor degeneration by inhibiting parthanatos

Abstract Photoreceptor degeneration is the hallmark of retinitis pigmentosa. Identifying general mechanisms underlying photoreceptor cell death is key to developing effective, mutation-independent treatments to prevent vision loss. Mitophagy is a protective pathway that prevents age-dependent vision...

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Bibliographic Details
Main Authors: Beatriz Villarejo-Zori, Juan Zapata-Muñoz, Elena Sierra-Filardi, Ignacio Ramírez-Pardo, Lambert Montava-Garriga, Ian G. Ganley, Patricia Boya
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07686-x
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