Knocking Out TAAR5: A Pathway to Enhanced Neurogenesis and Dopamine Signaling in the Striatum

Knocking Out TAAR5: A Pathway to Enhanced Neurogenesis and Dopamine Signaling in the Striatum

The member of trace-amine associated receptor family, TAAR5 receptor was suggested to recognize tertiary amines, mostly in the olfactory system; however, knocking out the receptor TAAR5 in mice showed an enhancing effect on adult neurogenesis and dopamine neurotransmission in the striatum. To estima...

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Main Authors: Anastasia N. Vaganova, Zoia S. Fesenko, Evgeniya V. Efimova, Sergei A. Chekrygin, Daria D. Shafranskaya, Andrey D. Prjibelski, Nataliia V. Katolikova, Raul R. Gainetdinov
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
trace amine-associated receptors
TAAR5
striatum
neurogenesis
dopamine
Online Access:https://www.mdpi.com/2073-4409/13/22/1910
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