Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee

Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee

Introduction In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL). It is desirable to select analgesics for elderly patients based on comparative data on an...

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Main Authors: Tempei Miyaji, Mototsugu Shimokawa, Hiroyuki Aono, Sadamoto Zenda, Makoto Endo, Yasuharu Nakashima, TOSHIHIKO HARA, Shinya Kawahara, Taishi Sato, Masami Tokunaga, Taro Mawatari, Tsutomu Kawano, Sanae Sakamoto, Toshio Takano, Masumi Miyake
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/2/e068220.full
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