Treating Facial Scars using Polydioxanone Threads

Summary: Traditional scar treatments, such as laser therapy, chemical peels, and surgery, are expensive and require long recovery times. Polydioxanone (PDO) threads offer a minimally invasive and cost-effective solution that enhances collagen production and skin texture.This study aimed to evaluate...

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Main Authors: Mohammad Khaled Hamolaila, Mazen Zenati, Asaad Shehada
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:JPRAS Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352587825000051
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author Mohammad Khaled Hamolaila
Mazen Zenati
Asaad Shehada
author_facet Mohammad Khaled Hamolaila
Mazen Zenati
Asaad Shehada
author_sort Mohammad Khaled Hamolaila
collection DOAJ
description Summary: Traditional scar treatments, such as laser therapy, chemical peels, and surgery, are expensive and require long recovery times. Polydioxanone (PDO) threads offer a minimally invasive and cost-effective solution that enhances collagen production and skin texture.This study aimed to evaluate the effectiveness of PDO threads in the management of atrophic facial scars due to the lack of clinical research on this topic.A prospective clinical study was conducted on 20 patients with facial atrophic scars caused by accidents or previous surgical procedures. The patient and observer scar assessment scale was used to evaluate the scars from the observer's and patient's perspectives at three-time points for each patient. The observer assessment included the following variables: vascularity, pigmentation, thickness, pliability, surface area, and homogeneity. The patient assessment included the following variables: pain, color, stiffness, thickness, appearance, and itching.Statistically significant improvement was observed in atrophic facial scars treated using PDO threads in all observer variables (p<0.001). Significant improvement was recorded in the patient's color, stiffness, thickness, and appearance variables; however, itching sensation increased between T0 and T1 with no statistically significant differences in the pain variable.Within the limits of this study, we conclude that PDO threads are known for ease of use, availability, and biocompatibility. They biodegrade naturally, reducing irritation risk. By stimulating collagen, PDO threads promote natural skin regeneration and thereby improve scars without using foreign materials. The treatment method is safe and minimally invasive, with short recovery times. Clinical studies showed significant improvements in atrophic facial scars with high patient satisfaction.
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spelling doaj-art-52e81a221c60405eaca975bc1c9fb77b2025-02-12T05:31:19ZengElsevierJPRAS Open2352-58782025-03-0143497505Treating Facial Scars using Polydioxanone ThreadsMohammad Khaled Hamolaila0Mazen Zenati1Asaad Shehada2Department of oral and maxillofacial surgery, Damascus university, Damascus, SyriaDepartment of oral and maxillofacial surgery, Damascus university, Damascus, SyriaCorresponding Author: +963994556568; Department of oral and maxillofacial surgery, Damascus university, Damascus, SyriaSummary: Traditional scar treatments, such as laser therapy, chemical peels, and surgery, are expensive and require long recovery times. Polydioxanone (PDO) threads offer a minimally invasive and cost-effective solution that enhances collagen production and skin texture.This study aimed to evaluate the effectiveness of PDO threads in the management of atrophic facial scars due to the lack of clinical research on this topic.A prospective clinical study was conducted on 20 patients with facial atrophic scars caused by accidents or previous surgical procedures. The patient and observer scar assessment scale was used to evaluate the scars from the observer's and patient's perspectives at three-time points for each patient. The observer assessment included the following variables: vascularity, pigmentation, thickness, pliability, surface area, and homogeneity. The patient assessment included the following variables: pain, color, stiffness, thickness, appearance, and itching.Statistically significant improvement was observed in atrophic facial scars treated using PDO threads in all observer variables (p<0.001). Significant improvement was recorded in the patient's color, stiffness, thickness, and appearance variables; however, itching sensation increased between T0 and T1 with no statistically significant differences in the pain variable.Within the limits of this study, we conclude that PDO threads are known for ease of use, availability, and biocompatibility. They biodegrade naturally, reducing irritation risk. By stimulating collagen, PDO threads promote natural skin regeneration and thereby improve scars without using foreign materials. The treatment method is safe and minimally invasive, with short recovery times. Clinical studies showed significant improvements in atrophic facial scars with high patient satisfaction.http://www.sciencedirect.com/science/article/pii/S2352587825000051Atrophic scarsPolydioxanone (PDO) threadsnon-surgical techniques
spellingShingle Mohammad Khaled Hamolaila
Mazen Zenati
Asaad Shehada
Treating Facial Scars using Polydioxanone Threads
JPRAS Open
Atrophic scars
Polydioxanone (PDO) threads
non-surgical techniques
title Treating Facial Scars using Polydioxanone Threads
title_full Treating Facial Scars using Polydioxanone Threads
title_fullStr Treating Facial Scars using Polydioxanone Threads
title_full_unstemmed Treating Facial Scars using Polydioxanone Threads
title_short Treating Facial Scars using Polydioxanone Threads
title_sort treating facial scars using polydioxanone threads
topic Atrophic scars
Polydioxanone (PDO) threads
non-surgical techniques
url http://www.sciencedirect.com/science/article/pii/S2352587825000051
work_keys_str_mv AT mohammadkhaledhamolaila treatingfacialscarsusingpolydioxanonethreads
AT mazenzenati treatingfacialscarsusingpolydioxanonethreads
AT asaadshehada treatingfacialscarsusingpolydioxanonethreads