Lactoferrin-osteopontin complexes: insights into intestinal organoid bioavailability and gut microbiota modulation

Lactoferrin-osteopontin complexes: insights into intestinal organoid bioavailability and gut microbiota modulation

Abstract Lactoferrin (LF) and osteopontin (OPN) are key bioactive milk proteins with significant immune-modulatory, gut, and systemic health benefits. We investigated the bioavailability and intestinal uptake dynamics of bovine LF-OPN soluble complexes (SC) and complex coacervates (CC) using a micro...

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Main Authors: Camilla Ceroni, Loïc Dayon, Pieter Van den Abbeele, Aline Roch, Juliane Dervaux, Marion Ernest, Pascaline Sirugue, Aurélien Baudot, Marine R.-C. Kraus, Nathalie Brandenberg, Jonathan O’Regan, David Goulding, Omid Mashinchian
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08460-7
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