Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa
Background: Despite the government’s effort to reduce the prevalence of anaemia among reproductive-age women globally, it continues as a significant public health issue, especially in low- and middle-income countries. Iron–folic acid (IFA) supplementation is a widely used intervention to prevent ana...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-02-01
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| Series: | Women's Health |
| Online Access: | https://doi.org/10.1177/17455057251317547 |
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| _version_ | 1823860040384118784 |
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| author | Melaku Tadege Engidaw Patricia Lee Faruk Ahmed |
| author_facet | Melaku Tadege Engidaw Patricia Lee Faruk Ahmed |
| author_sort | Melaku Tadege Engidaw |
| collection | DOAJ |
| description | Background: Despite the government’s effort to reduce the prevalence of anaemia among reproductive-age women globally, it continues as a significant public health issue, especially in low- and middle-income countries. Iron–folic acid (IFA) supplementation is a widely used intervention to prevent anaemia, but compliance remains a major challenge. There is a lack of literature examining IFA supplementation compliance during pregnancy and its impact on preventing and controlling anaemia during post-pregnancy in the East Africa region. Objective: This study aims to investigate compliance with IFA supplementation during pregnancy and its impact on post-pregnancy anaemia among reproductive-age women in East Africa. Design: This study was designed as a cross-sectional survey. Methods: This study used data from 43,200 reproductive-age women from 2015 to 2022 demographic and health survey datasets. We used multilevel mixed-effect logistic regression analysis to identify associated factors with IFA supplementation compliance during pregnancy. Furthermore, a propensity score matching (PSM) analysis was used to determine the effect of IFA supplementation compliance on anaemia after pregnancy among women. Results: The level of compliance with IFA supplementation during pregnancy was 31.33% (95% confidence interval (CI): 30.89, 31.77), whereas the prevalence of anaemia among reproductive-age women was 32.08% (95% CI: 31.64, 32.52). Maternal education, the timing of antenatal care (ANC) visits, wanted index pregnancy (last pregnancy), wealth status, healthcare access, mass media exposure and ANC services from skilled healthcare providers were significantly associated with compliance with IFA supplementation among pregnant women. The PSM analysis indicated a significant positive association between IFA supplementation compliance during pregnancy and prevention of post-pregnancy anaemia among reproductive-age women, with an average treatment effect on the treated (ATT) of 25.55% (ATT = −0.2555, 95% CI: −0.3440, −0.1669, p < 0.0001). Conclusion: Despite universal IFA supplementation, anaemia remains prevalent in East African countries due to low level of compliance with IFA supplementation. Targeting individual and socio-economic factors during IFA supplementation promotion helps to prevent anaemia after pregnancy. Further research is recommended to gain deeper insights. |
| format | Article |
| id | doaj-art-52dac48b49154fb0ba96c2b426175409 |
| institution | Kabale University |
| issn | 1745-5065 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Women's Health |
| spelling | doaj-art-52dac48b49154fb0ba96c2b4261754092025-02-10T17:03:20ZengSAGE PublishingWomen's Health1745-50652025-02-012110.1177/17455057251317547Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East AfricaMelaku Tadege Engidaw0Patricia Lee1Faruk Ahmed2Department of Public Health (Human Nutrition), College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Medical Research, China Medical University Hospital, Taichung City, TaiwanPublic Health, School of Medicine and Dentistry, Gold Coast Campus, Griffith University, Gold Coast, QLD, AustraliaBackground: Despite the government’s effort to reduce the prevalence of anaemia among reproductive-age women globally, it continues as a significant public health issue, especially in low- and middle-income countries. Iron–folic acid (IFA) supplementation is a widely used intervention to prevent anaemia, but compliance remains a major challenge. There is a lack of literature examining IFA supplementation compliance during pregnancy and its impact on preventing and controlling anaemia during post-pregnancy in the East Africa region. Objective: This study aims to investigate compliance with IFA supplementation during pregnancy and its impact on post-pregnancy anaemia among reproductive-age women in East Africa. Design: This study was designed as a cross-sectional survey. Methods: This study used data from 43,200 reproductive-age women from 2015 to 2022 demographic and health survey datasets. We used multilevel mixed-effect logistic regression analysis to identify associated factors with IFA supplementation compliance during pregnancy. Furthermore, a propensity score matching (PSM) analysis was used to determine the effect of IFA supplementation compliance on anaemia after pregnancy among women. Results: The level of compliance with IFA supplementation during pregnancy was 31.33% (95% confidence interval (CI): 30.89, 31.77), whereas the prevalence of anaemia among reproductive-age women was 32.08% (95% CI: 31.64, 32.52). Maternal education, the timing of antenatal care (ANC) visits, wanted index pregnancy (last pregnancy), wealth status, healthcare access, mass media exposure and ANC services from skilled healthcare providers were significantly associated with compliance with IFA supplementation among pregnant women. The PSM analysis indicated a significant positive association between IFA supplementation compliance during pregnancy and prevention of post-pregnancy anaemia among reproductive-age women, with an average treatment effect on the treated (ATT) of 25.55% (ATT = −0.2555, 95% CI: −0.3440, −0.1669, p < 0.0001). Conclusion: Despite universal IFA supplementation, anaemia remains prevalent in East African countries due to low level of compliance with IFA supplementation. Targeting individual and socio-economic factors during IFA supplementation promotion helps to prevent anaemia after pregnancy. Further research is recommended to gain deeper insights.https://doi.org/10.1177/17455057251317547 |
| spellingShingle | Melaku Tadege Engidaw Patricia Lee Faruk Ahmed Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa Women's Health |
| title | Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa |
| title_full | Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa |
| title_fullStr | Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa |
| title_full_unstemmed | Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa |
| title_short | Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa |
| title_sort | iron and folic acid supplementation compliance during pregnancy and its effect on post pregnancy anaemia among reproductive age women in east africa |
| url | https://doi.org/10.1177/17455057251317547 |
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