A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh

We consider a deterministic optimal control approach with cost-effectiveness analysis for the diphtheria outbreak in the Rohingya refugee camp in Bangladesh. A deterministic epidemic dynamical model for diphtheria outbreaks has been developed with three optimal controls: vaccination, latent, and inf...

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Main Authors: Zahurul Islam, K. M. Ariful Kabir, M. M. Rahman, Md. Atikur Rahman
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2024/6654346
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author Zahurul Islam
K. M. Ariful Kabir
M. M. Rahman
Md. Atikur Rahman
author_facet Zahurul Islam
K. M. Ariful Kabir
M. M. Rahman
Md. Atikur Rahman
author_sort Zahurul Islam
collection DOAJ
description We consider a deterministic optimal control approach with cost-effectiveness analysis for the diphtheria outbreak in the Rohingya refugee camp in Bangladesh. A deterministic epidemic dynamical model for diphtheria outbreaks has been developed with three optimal controls: vaccination, latent, and infectious treatment. Here, the qualitative study of the model has been interpreted. An objective function has been regarded as a cost function introduced by the optimal controls and the diseases themselves. Then, the existence and uniqueness of the optimal system have also been shown with the help of Pontryagin’s minimum principle. A numerical investigation has been carried out to solve the state and adjoint systems of optimality conditions. Furthermore, it has been investigated using several levels of availability of the optimal controls (vaccination, latent, and infectious treatment) to identify which level gives the best outcomes. Moreover, the cost-effective analysis has been inquired with the numerical value of the cost function and the total cured population in each control strategy to clarify the strategy with the least cost but maximum remediation.
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institution Kabale University
issn 1099-0526
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publishDate 2024-01-01
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series Complexity
spelling doaj-art-52d9f9a21d394f31ac01036d91cad2662025-02-03T07:23:39ZengWileyComplexity1099-05262024-01-01202410.1155/2024/6654346A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in BangladeshZahurul Islam0K. M. Ariful Kabir1M. M. Rahman2Md. Atikur Rahman3Department of MathematicsDepartment of MathematicsDepartment of MathematicsDepartment of Computer Science and EngineeringWe consider a deterministic optimal control approach with cost-effectiveness analysis for the diphtheria outbreak in the Rohingya refugee camp in Bangladesh. A deterministic epidemic dynamical model for diphtheria outbreaks has been developed with three optimal controls: vaccination, latent, and infectious treatment. Here, the qualitative study of the model has been interpreted. An objective function has been regarded as a cost function introduced by the optimal controls and the diseases themselves. Then, the existence and uniqueness of the optimal system have also been shown with the help of Pontryagin’s minimum principle. A numerical investigation has been carried out to solve the state and adjoint systems of optimality conditions. Furthermore, it has been investigated using several levels of availability of the optimal controls (vaccination, latent, and infectious treatment) to identify which level gives the best outcomes. Moreover, the cost-effective analysis has been inquired with the numerical value of the cost function and the total cured population in each control strategy to clarify the strategy with the least cost but maximum remediation.http://dx.doi.org/10.1155/2024/6654346
spellingShingle Zahurul Islam
K. M. Ariful Kabir
M. M. Rahman
Md. Atikur Rahman
A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
Complexity
title A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
title_full A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
title_fullStr A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
title_full_unstemmed A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
title_short A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
title_sort cost effective epidemiological exposition of diphtheria outbreak by the optimal control model a case study of rohingya refugee camp in bangladesh
url http://dx.doi.org/10.1155/2024/6654346
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