Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice.

Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice.

We tested the hypothesis that changing the gut microbiota using pectic oligosaccharides (POS) or inulin (INU) differently modulates the progression of leukemia and related metabolic disorders. Mice were transplanted with Bcr-Abl-transfected proB lymphocytes mimicking leukemia and received either POS...

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Main Authors: Laure B Bindels, Audrey M Neyrinck, Nuria Salazar, Bernard Taminiau, Céline Druart, Giulio G Muccioli, Emmanuelle François, Christophe Blecker, Aurore Richel, Georges Daube, Jacques Mahillon, Clara G de los Reyes-Gavilán, Patrice D Cani, Nathalie M Delzenne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0131009&type=printable
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