Transverse facial artery occlusion following hyaluronic acid and calcium hydroxyapatite filler injection: a case report

This case report describes a complication following the use of a filler composed of hyaluronic acid and calcium hydroxyapatite mixed in the same syringe, resulting in vascular occlusion of the right transverse facial artery. The patient developed hypopigmented macules, followed by a reticulated patt...

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Bibliographic Details
Main Authors: Isabelle Ary Duque, Francisco Jefferson Araújo Elias, Matheus Morais Lima
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia (SBD) 2025-04-01
Series:Surgical & Cosmetic Dermatology
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Online Access:http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v17/en_v17e20240352
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Summary:This case report describes a complication following the use of a filler composed of hyaluronic acid and calcium hydroxyapatite mixed in the same syringe, resulting in vascular occlusion of the right transverse facial artery. The patient developed hypopigmented macules, followed by a reticulated pattern and pustules. Treatment included prednisone, enoxaparin, and hyaluronidase. Due to worsening symptoms, including arterial obstruction confirmed by ultrasound, ultrasound-guided hyaluronidase injection and hyperbaric oxygen therapy were administered. The patient showed a favorable recovery, with regression of vascular complications. This case underscores the importance of early identification and intervention to minimize complications associated with vascular occlusion in aesthetic procedures.
ISSN:1984-8773