Opening new frontiers with catalytic nucleic acids in miRNA inhibition

Opening new frontiers with catalytic nucleic acids in miRNA inhibition

The concept of utilizing synthetic nucleic acids and their conjugates with biologically active molecules as RNA-targeted therapeutic agents represents a powerful strategy in the treatment of human pathologies. Recent research demonstrates that neoplastic development is closely associated with dysreg...

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Bibliographic Details
Main Authors: Olga Patutina, Svetlana Miroshnichenko, Daria Chiglintseva, Marina Zenkova
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
catalytic nucleic acids
miRNA
antimiRs
DNAzyme
ribozyme
antimiRzymes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1604711/full
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