How do immune cells shape type 1 diabetes? Insights from Mendelian randomization

How do immune cells shape type 1 diabetes? Insights from Mendelian randomization

ObjectiveThe role of immune cells in type 1 diabetes (T1D) is unclear. The aim of this study was to assess the causal effect of different immune cells on T1D using Mendelian randomization (MR).MethodsA dataset of immune cell phenotypes (numbered from GCST0001391 to GCST0002121) was obtained from the...

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Bibliographic Details
Main Authors: Yunfeng Yu, Xinyu Yang, Juan Deng, Jingyi Wu, Siyang Bai, Rong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Endocrinology
Subjects:
immune cell
phenotype
type 1 diabetes
GWAS
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1402956/full
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