Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity.

Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity.

Hepatitis C Virus (HCV) is a major public health concern, with no effective vaccines currently available and 3% of the world's population being infected. Despite the existence of both B- and T-cell immunity in HCV-infected patients, chronic viral infection and HCV-related malignancies progress....

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Bibliographic Details
Main Authors: Yi Zhang, Yeuying Liu, Kelly M Moxley, Lucy Golden-Mason, Michael G Hughes, Tongxin Liu, Mirjam H M Heemskerk, Hugo R Rosen, Michael I Nishimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001018&type=printable
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