Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial
Abstract Background Adhesion formation poses a significant challenge for both patients and hand surgeons following tendon repair. One common strategy to prevent adhesion formation is the use of physical barriers. This study aimed to compare the outcomes of extensor tendon repair with and without the...
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BMC
2025-01-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-024-08241-z |
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| author | Abbas Abdoli Tafti Hamidreza Mohammadi Morteza Rezaei Seyyed Hossein Saeed Bonadaki |
| author_facet | Abbas Abdoli Tafti Hamidreza Mohammadi Morteza Rezaei Seyyed Hossein Saeed Bonadaki |
| author_sort | Abbas Abdoli Tafti |
| collection | DOAJ |
| description | Abstract Background Adhesion formation poses a significant challenge for both patients and hand surgeons following tendon repair. One common strategy to prevent adhesion formation is the use of physical barriers. This study aimed to compare the outcomes of extensor tendon repair with and without the application of the OrthoWrap® bioresorbable Sheet, specifically in terms of adhesion prevention. Methods This triple-blind randomized clinical trial was conducted on patients with trauma to the extensor zone VI tendons. Participants were randomly assigned to one of two groups. In the intervention group, OrthoWrap® bioresorbable Sheet was applied in addition to the standard tendon repair protocol. Over a three-month follow-up period, the Visual Analogue Scale (VAS) score, extension lag, and metacarpophalangeal joint flexion were assessed. Additionally, the mobility of the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints was evaluated using the Strickland classification. Results A total of 42 patients in the OrthoWrap® group and 43 in the control group were evaluated over the three-month period. Both groups showed a significant reduction in mean extension lag at the metacarpophalangeal joint over time. No significant condition-by-time interactions were found for MP joint flexion or VAS scores (p > 0.05). However, significant improvements in MP joint flexion and VAS scores were observed over time. The OrthoWrap® group demonstrated significantly more favorable outcomes compared to the control group. Conclusion The clinical application of OrthoWrap® in extensor tendon repair demonstrated statistically significant but modest improvements in extension lag (2.5°). While patients treated with OrthoWrap® showed better outcomes in Strickland’s classification, the clinical significance of these small differences and their impact on patient function requires further investigation. Trial registration IRCT, IRCT20180627040252N3. Registered 20,220,617, Https//irct.behdasht.gov.ir/trial/56,652. |
| format | Article |
| id | doaj-art-529d943d336f4fb994c73136ff1771a5 |
| institution | Kabale University |
| issn | 1471-2474 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-529d943d336f4fb994c73136ff1771a52025-01-05T12:05:00ZengBMCBMC Musculoskeletal Disorders1471-24742025-01-012611910.1186/s12891-024-08241-zUse of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trialAbbas Abdoli Tafti0Hamidreza Mohammadi1Morteza Rezaei2Seyyed Hossein Saeed Bonadaki3Orthopedic Department, Shahid Sadoughi University of Medical SciencesOrthopedic Department, Shahid Sadoughi University of Medical SciencesOrthopedic Department, Hormozgan University of Medical SciencesOrthopedic Department, Shahid Sadoughi University of Medical SciencesAbstract Background Adhesion formation poses a significant challenge for both patients and hand surgeons following tendon repair. One common strategy to prevent adhesion formation is the use of physical barriers. This study aimed to compare the outcomes of extensor tendon repair with and without the application of the OrthoWrap® bioresorbable Sheet, specifically in terms of adhesion prevention. Methods This triple-blind randomized clinical trial was conducted on patients with trauma to the extensor zone VI tendons. Participants were randomly assigned to one of two groups. In the intervention group, OrthoWrap® bioresorbable Sheet was applied in addition to the standard tendon repair protocol. Over a three-month follow-up period, the Visual Analogue Scale (VAS) score, extension lag, and metacarpophalangeal joint flexion were assessed. Additionally, the mobility of the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints was evaluated using the Strickland classification. Results A total of 42 patients in the OrthoWrap® group and 43 in the control group were evaluated over the three-month period. Both groups showed a significant reduction in mean extension lag at the metacarpophalangeal joint over time. No significant condition-by-time interactions were found for MP joint flexion or VAS scores (p > 0.05). However, significant improvements in MP joint flexion and VAS scores were observed over time. The OrthoWrap® group demonstrated significantly more favorable outcomes compared to the control group. Conclusion The clinical application of OrthoWrap® in extensor tendon repair demonstrated statistically significant but modest improvements in extension lag (2.5°). While patients treated with OrthoWrap® showed better outcomes in Strickland’s classification, the clinical significance of these small differences and their impact on patient function requires further investigation. Trial registration IRCT, IRCT20180627040252N3. Registered 20,220,617, Https//irct.behdasht.gov.ir/trial/56,652.https://doi.org/10.1186/s12891-024-08241-zTendon RepairExtensor TendonOrthoWrapBarrier Film |
| spellingShingle | Abbas Abdoli Tafti Hamidreza Mohammadi Morteza Rezaei Seyyed Hossein Saeed Bonadaki Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial BMC Musculoskeletal Disorders Tendon Repair Extensor Tendon OrthoWrap Barrier Film |
| title | Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial |
| title_full | Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial |
| title_fullStr | Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial |
| title_full_unstemmed | Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial |
| title_short | Use of a bioresorbable polylactide sheet (OrthoWrap® Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial |
| title_sort | use of a bioresorbable polylactide sheet orthowrap r bioresorbable sheet on tendon healing after extensor tendon repair a controlled clinical trial |
| topic | Tendon Repair Extensor Tendon OrthoWrap Barrier Film |
| url | https://doi.org/10.1186/s12891-024-08241-z |
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