Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry
This paper describes a simple, rapid, and effective quality assessment method for Fructus Schisandrae by gas chromatography-mass spectrum (GC-MS). The method was established by using specific lignan fingerprint profiles and quantitation of characteristic compounds in this herbal medicine. The GC-MS...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/806759 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563059761086464 |
|---|---|
| author | Yong-Gang Xia Bing-You Yang Jun Liang Qi Yang Di Wang Hai-Xue Kuang |
| author_facet | Yong-Gang Xia Bing-You Yang Jun Liang Qi Yang Di Wang Hai-Xue Kuang |
| author_sort | Yong-Gang Xia |
| collection | DOAJ |
| description | This paper describes a simple, rapid, and effective quality assessment method for Fructus Schisandrae by gas chromatography-mass spectrum (GC-MS). The method was established by using specific lignan fingerprint profiles and quantitation of characteristic compounds in this herbal medicine. The GC-MS fingerprints of 15 batches of Schisandra samples from different regions of China showed similar lignan profiles. Five peaks were selected as characteristic peaks, and all of these were identified by using GC-MS techniques. The relative retention times of these characteristic peaks in the GC-MS fingerprint were established as an important parameter for identification of Schisandra samples. Meanwhile, relative peak areas may be a feasible approach to discriminate the S. chinensis and S. sphenanthera. Finally, these pharmacologically active constituents in the titled plant, schisandrins A–C and schizandrols A and B, were quantitatively determined using a validated GC-MS method. |
| format | Article |
| id | doaj-art-5296be2044cb4316890a01986e761fca |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-5296be2044cb4316890a01986e761fca2025-02-03T01:21:06ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/806759806759Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass SpectrometryYong-Gang Xia0Bing-You Yang1Jun Liang2Qi Yang3Di Wang4Hai-Xue Kuang5Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaKey Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaKey Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaKey Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaKey Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaKey Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, ChinaThis paper describes a simple, rapid, and effective quality assessment method for Fructus Schisandrae by gas chromatography-mass spectrum (GC-MS). The method was established by using specific lignan fingerprint profiles and quantitation of characteristic compounds in this herbal medicine. The GC-MS fingerprints of 15 batches of Schisandra samples from different regions of China showed similar lignan profiles. Five peaks were selected as characteristic peaks, and all of these were identified by using GC-MS techniques. The relative retention times of these characteristic peaks in the GC-MS fingerprint were established as an important parameter for identification of Schisandra samples. Meanwhile, relative peak areas may be a feasible approach to discriminate the S. chinensis and S. sphenanthera. Finally, these pharmacologically active constituents in the titled plant, schisandrins A–C and schizandrols A and B, were quantitatively determined using a validated GC-MS method.http://dx.doi.org/10.1155/2014/806759 |
| spellingShingle | Yong-Gang Xia Bing-You Yang Jun Liang Qi Yang Di Wang Hai-Xue Kuang Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry The Scientific World Journal |
| title | Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry |
| title_full | Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry |
| title_fullStr | Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry |
| title_full_unstemmed | Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry |
| title_short | Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry |
| title_sort | quantitative analysis and fingerprint profiles for quality control of fructus schisandrae by gas chromatography mass spectrometry |
| url | http://dx.doi.org/10.1155/2014/806759 |
| work_keys_str_mv | AT yonggangxia quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry AT bingyouyang quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry AT junliang quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry AT qiyang quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry AT diwang quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry AT haixuekuang quantitativeanalysisandfingerprintprofilesforqualitycontroloffructusschisandraebygaschromatographymassspectrometry |