Forskolin attenuates doxorubicin-induced cardiotoxicity by activating SIRT1/FOXO1/PINK1/Parkin-mediated mitophagy
Background: Despite the advancement of cancer therapy, chemotherapy is still a standard approach in cancer treatment. Doxorubicin (DXR) is a potent chemotherapeutic drug, used for the treatment of both adult and pediatric cancers. However, its clinical use is limited due to acute and chronic cardiot...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Scientific African |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227625002340 |
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