Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix
We suggest sensor systems based on the gold and silver nanoparticles embedded within the polymethacrylate matrix (PMM) for colorimetric determination of glucose. A feature of such sensors is the exclusion of the use of toxic solvents in their manufacture and application. In addition, silver and gold...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Green Analytical Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772577425000746 |
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| author | Nadezhda V. Saranchina Olga A. Bazhenova Dmitrii A. Shcherbakov Nataliya A. Gavrilenko Kirill V. Serebriakov Darya E. Kuznetsova Mikhail A. Gavrilenko |
| author_facet | Nadezhda V. Saranchina Olga A. Bazhenova Dmitrii A. Shcherbakov Nataliya A. Gavrilenko Kirill V. Serebriakov Darya E. Kuznetsova Mikhail A. Gavrilenko |
| author_sort | Nadezhda V. Saranchina |
| collection | DOAJ |
| description | We suggest sensor systems based on the gold and silver nanoparticles embedded within the polymethacrylate matrix (PMM) for colorimetric determination of glucose. A feature of such sensors is the exclusion of the use of toxic solvents in their manufacture and application. In addition, silver and gold nanoparticles are stabilized in a solid transparent polymer, which prevents migration into the environment. We studied the conditions of interaction between the gold and silver nanoparticles and matrix components by evaluating the influence of such factors as solution pH, the amount of nanoparticles within the polymer matrix, the contact time, and the analyte concentration upon the analytical signal. Dual-signal spectrophotometric and colorimetric approaches of using PMM-Ag0 / PMM-Au° can be used for the determination of glucose in saliva in the range of 0.1–5.6 mM with the limit of detection of 0.04 mM and 0.1–1.0 mM with the limit of detection of 0.03 mM, accordingly. |
| format | Article |
| id | doaj-art-528eaa7ec116447d9d90cb1b9a05005e |
| institution | DOAJ |
| issn | 2772-5774 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Green Analytical Chemistry |
| spelling | doaj-art-528eaa7ec116447d9d90cb1b9a05005e2025-08-20T03:10:27ZengElsevierGreen Analytical Chemistry2772-57742025-06-011310027810.1016/j.greeac.2025.100278Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrixNadezhda V. Saranchina0Olga A. Bazhenova1Dmitrii A. Shcherbakov2Nataliya A. Gavrilenko3Kirill V. Serebriakov4Darya E. Kuznetsova5Mikhail A. Gavrilenko6Tomsk Polytechnic University, 634050 Tomsk, Russian FederationTomsk Polytechnic University, 634050 Tomsk, Russian FederationTomsk State University, 634050 Tomsk, Russian FederationTomsk State University, 634050 Tomsk, Russian FederationTomsk Polytechnic University, 634050 Tomsk, Russian FederationTomsk State University, 634050 Tomsk, Russian FederationTomsk Polytechnic University, 634050 Tomsk, Russian Federation; Corresponding author.We suggest sensor systems based on the gold and silver nanoparticles embedded within the polymethacrylate matrix (PMM) for colorimetric determination of glucose. A feature of such sensors is the exclusion of the use of toxic solvents in their manufacture and application. In addition, silver and gold nanoparticles are stabilized in a solid transparent polymer, which prevents migration into the environment. We studied the conditions of interaction between the gold and silver nanoparticles and matrix components by evaluating the influence of such factors as solution pH, the amount of nanoparticles within the polymer matrix, the contact time, and the analyte concentration upon the analytical signal. Dual-signal spectrophotometric and colorimetric approaches of using PMM-Ag0 / PMM-Au° can be used for the determination of glucose in saliva in the range of 0.1–5.6 mM with the limit of detection of 0.04 mM and 0.1–1.0 mM with the limit of detection of 0.03 mM, accordingly.http://www.sciencedirect.com/science/article/pii/S2772577425000746GlucoseGold nanoparticlesSilver nanoparticlesPolymethacrylate matrixSolid phase spectrophotometryDigital colorimetry |
| spellingShingle | Nadezhda V. Saranchina Olga A. Bazhenova Dmitrii A. Shcherbakov Nataliya A. Gavrilenko Kirill V. Serebriakov Darya E. Kuznetsova Mikhail A. Gavrilenko Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix Green Analytical Chemistry Glucose Gold nanoparticles Silver nanoparticles Polymethacrylate matrix Solid phase spectrophotometry Digital colorimetry |
| title | Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| title_full | Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| title_fullStr | Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| title_full_unstemmed | Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| title_short | Dual-mode glucose sensing: Colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| title_sort | dual mode glucose sensing colorimetric chemical sensors using silver or gold nanoparticles embedded within polymethacrylate matrix |
| topic | Glucose Gold nanoparticles Silver nanoparticles Polymethacrylate matrix Solid phase spectrophotometry Digital colorimetry |
| url | http://www.sciencedirect.com/science/article/pii/S2772577425000746 |
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