Correction of depressive-like state in rats induced by social stress using a new 3-substituted thietane-1,1-dioxide derivative

Correction of depressive-like state in rats induced by social stress using a new 3-substituted thietane-1,1-dioxide derivative

Introduction. Among the various animal models of depression used to study the pathogenesis of depression and to evaluate the antidepressant action of new compounds, models based on social stress are characterized by high constructive, face and predictive validity. The rat model of depression based o...

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Bibliographic Details
Main Authors: G. G. Gaisina, I. L. Nikitina, E. E. Klen, R. A. Karaguzin, A. V. Samorodov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-03-01
Series:Разработка и регистрация лекарственных средств
Subjects:
thietane
antidepressive agents
social defeat
rats
depression
Online Access:https://www.pharmjournal.ru/jour/article/view/2037
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