Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.

Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis. In breast cancer, non-canonical Wnt signaling by Wnt5a has been reported to antagonize tumor growth. He...

Full description

Saved in:
Bibliographic Details
Main Authors: Randall A Dass, Aishe A Sarshad, Brittany B Carson, Jennifer M Feenstra, Amanpreet Kaur, Ales Obrdlik, Matthew M Parks, Varsha Prakash, Damon K Love, Kristian Pietras, Rosa Serra, Scott C Blanchard, Piergiorgio Percipalle, Anthony M C Brown, C Theresa Vincent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006217&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items