Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C

Trimethylaminuria (TMAU), also known as fish odor syndrome, is a rare metabolic disorder resulting from a deficiency in the enzyme flavin-containing monooxygenase 3, which is responsible for the detoxification of trimethylamine produced during the metabolism of certain foods. This case report descri...

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Main Author: Martina Knapp
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-06-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5520
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author Martina Knapp
author_facet Martina Knapp
author_sort Martina Knapp
collection DOAJ
description Trimethylaminuria (TMAU), also known as fish odor syndrome, is a rare metabolic disorder resulting from a deficiency in the enzyme flavin-containing monooxygenase 3, which is responsible for the detoxification of trimethylamine produced during the metabolism of certain foods. This case report describes a 58-year-old male who presented with a sudden onset of fish-like body odor, diagnosed with secondary TMAU likely triggered by liver cirrhosis and dietary supplements. The report outlines the clinical presentation, diagnostic approach, and management strategies for this rare condition.
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series European Journal of Case Reports in Internal Medicine
spelling doaj-art-527369eefdbf4d8384f8c44bd0ec2f732025-08-20T02:37:32ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-06-0110.12890/2025_0055205055Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis CMartina Knapp0Praxis 54, Primary Care Clinic, Pfaeffikon, SwitzerlandTrimethylaminuria (TMAU), also known as fish odor syndrome, is a rare metabolic disorder resulting from a deficiency in the enzyme flavin-containing monooxygenase 3, which is responsible for the detoxification of trimethylamine produced during the metabolism of certain foods. This case report describes a 58-year-old male who presented with a sudden onset of fish-like body odor, diagnosed with secondary TMAU likely triggered by liver cirrhosis and dietary supplements. The report outlines the clinical presentation, diagnostic approach, and management strategies for this rare condition.https://www.ejcrim.com/index.php/EJCRIM/article/view/5520trimethylaminuriafish odor syndromesecondary tmautmaocarnitine supplements
spellingShingle Martina Knapp
Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
European Journal of Case Reports in Internal Medicine
trimethylaminuria
fish odor syndrome
secondary tmau
tmao
carnitine supplements
title Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
title_full Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
title_fullStr Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
title_full_unstemmed Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
title_short Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
title_sort trimethylaminuria in a 58 year old male with liver cirrhosis and hepatitis c
topic trimethylaminuria
fish odor syndrome
secondary tmau
tmao
carnitine supplements
url https://www.ejcrim.com/index.php/EJCRIM/article/view/5520
work_keys_str_mv AT martinaknapp trimethylaminuriaina58yearoldmalewithlivercirrhosisandhepatitisc