Efficacy of mesenchymal stem cell-based therapies in the treatment of perianal fistulizing Crohn’s disease: a systematic review and meta-analysis

Efficacy of mesenchymal stem cell-based therapies in the treatment of perianal fistulizing Crohn’s disease: a systematic review and meta-analysis

Abstract Background Perianal lesions of Crohn’s disease (CD) are complex and disabling conditions. Mesenchymal stem cell (MSC)-based therapies have emerged as an innovative approach in managing refractory perianal fistulizing CD. We conducted a systematic review and meta-analysis to describe and com...

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Bibliographic Details
Main Authors: Lucas Guillo, Robinson Gravier Dumonceau, Mélanie Vélier, Mélanie Serrero, Fanny Grimaud, Florence Sabatier, Jérémy Magalon
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Stem Cell Research & Therapy
Subjects:
Crohn’s disease
Fistula
Mesenchymal stem cells
Stromal vascular fraction
Meta-analysis
Online Access:https://doi.org/10.1186/s13287-025-04272-y
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