COMORBIDITY IN PATIENTS WITH RHEUMATOID ARTHRITIS

Objective: to study the pattern and rate of comorbid diseases in patients with rheumatoid  arthritis (RA) in the Saratov Region.Subjects and methods. The investigation enrolled 328 RA patients treated at the Rheumatology Unit, Saratov Regional   Clinical Hospital,  in 2011 to 2013. RA was diagnosed...

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Main Authors: N. M. Nikitina, I. A. Afanasyev, A. P. Rebrov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2015-04-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/2069
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Summary:Objective: to study the pattern and rate of comorbid diseases in patients with rheumatoid  arthritis (RA) in the Saratov Region.Subjects and methods. The investigation enrolled 328 RA patients treated at the Rheumatology Unit, Saratov Regional   Clinical Hospital,  in 2011 to 2013. RA was diagnosed using the 1987 ACR criteria and the 2010 ACR/EULAR ones. The investigation included the patients receiving disease-modifying antirheumatic drugs (DMARD) at a stable dose for 3 months or longer. A questionnaire  survey and objective examination  were made in the patients; data from their medical records were taken into account.Results and discussion. Comorbidities  were identified in 86.6% of the patients; 57.9% had a concurrence of two or more comorbid conditions.  Osteoarthritis,  hypertension, and coronary heart disease were detected in 50.7, 57.7, and 30.9% of the RA patients, respectively. Out of the inflammatory diseases, gastrointestinal  tract lesion was most common (80.3%); urinary tract infections were slightly less common  (19.7%).Conclusion. The high rate of comorbidity was noted in patients with RA. The pattern of comorbidities shows a preponderance  of hypertension  and osteoarthritis  and an exacerbation of gastrointestinal  and urinary tract diseases frequently makes the choice of DMARD  difficult.
ISSN:1995-4484
1995-4492