P-Rex1 Expression in Invasive Breast Cancer in relation to Receptor Status and Distant Metastatic Site

P-Rex1 Expression in Invasive Breast Cancer in relation to Receptor Status and Distant Metastatic Site

Background. Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (P-Rex1) has been implicated in cancer growth, metastasis, and response to phosphatidylinositol 3-kinase (PI3K) inhibitor therapy. The aim of this study was to determine whether P-Rex1 expression differs between pri...

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Bibliographic Details
Main Authors: Jonathan D. Marotti, Kristen E. Muller, Laura J. Tafe, Eugene Demidenko, Todd W. Miller
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2017/4537532
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