Facile indazole-endowed thiadiazole hybrid derivatives as antibacterial, anti-diabetic and thymidine phosphorylase inhibitors: An insight to experimental, in-vitro biological potential and computational approaches
Abstract In this study, a series of newly synthesized indazole-based thiadiazole hybrid derivatives (1–13) were successfully synthesized from indazole-based thiosemicarbazides starting from the 5-methyl-1H-indazole-3-carboxylic acid. The structure of the synthesized compounds were confirmed through...
Saved in:
| Main Authors: | Sabeen Arshad, Aneela Maalik, Wajid Rehman, Yousaf Khan, Mohammed M. Alanazi, Hina Sarfraz, Liaqat Rasheed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
|
| Series: | Saudi Pharmaceutical Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44446-025-00003-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features
by: E. M. Bakurova, et al.
Published: (2015-04-01) -
The diagnostic value of IL-6 and thymidine phosphorylase in the progression of osteosarcoma
by: Bushra AM Abdul Azeez, et al.
Published: (2025-04-01) -
Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy
by: Bo Huang, et al.
Published: (2025-04-01) -
Correction: Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy
by: Bo Huang, et al.
Published: (2025-07-01) -
Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab
by: Masatsune Shibutani, et al.
Published: (2025-01-01)