Diarrhoea in Patients with COVID-19

Aim. Revision of possible causes of diarrhoea in patients with the COVID-19 infection.Key points. Apart from respiratory symptoms, patients with the COVID-19 infection may also express gastrointestinal complaints, more frequently of diarrhoea (2–40% incidence rate). The causes of diarrhoea may relat...

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Main Author: A. A. Sheptulin
Format: Article
Language:Russian
Published: Gastro LLC 2020-12-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/520
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author A. A. Sheptulin
author_facet A. A. Sheptulin
author_sort A. A. Sheptulin
collection DOAJ
description Aim. Revision of possible causes of diarrhoea in patients with the COVID-19 infection.Key points. Apart from respiratory symptoms, patients with the COVID-19 infection may also express gastrointestinal complaints, more frequently of diarrhoea (2–40% incidence rate). The causes of diarrhoea may relate to the virus direct interaction with the angiotensin-converting enzyme 2 (ACE2) receptors in mucosa, its impact on the intestinal microbiota and therapeutic side effects. The possible occurrence of diarrhoea as a leading clinical manifestation of the coronavirus infection hampers its timely diagnosis. Published evidence on the impact of diarrhoea on the course of COVID-19 is contradictory.Conclusion. Epidemiological and clinical aspects of this problem require further research.
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-5252439743c8485ea0183ec6896aca0e2025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-12-01306515610.22416/1382-4376-2020-30-6-51-56403Diarrhoea in Patients with COVID-19A. A. Sheptulin0Sechenov First Moscow State Medical University (Sechenov University)Aim. Revision of possible causes of diarrhoea in patients with the COVID-19 infection.Key points. Apart from respiratory symptoms, patients with the COVID-19 infection may also express gastrointestinal complaints, more frequently of diarrhoea (2–40% incidence rate). The causes of diarrhoea may relate to the virus direct interaction with the angiotensin-converting enzyme 2 (ACE2) receptors in mucosa, its impact on the intestinal microbiota and therapeutic side effects. The possible occurrence of diarrhoea as a leading clinical manifestation of the coronavirus infection hampers its timely diagnosis. Published evidence on the impact of diarrhoea on the course of COVID-19 is contradictory.Conclusion. Epidemiological and clinical aspects of this problem require further research.https://www.gastro-j.ru/jour/article/view/520covid-19diarrhoeadevelopmental mechanisms
spellingShingle A. A. Sheptulin
Diarrhoea in Patients with COVID-19
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
covid-19
diarrhoea
developmental mechanisms
title Diarrhoea in Patients with COVID-19
title_full Diarrhoea in Patients with COVID-19
title_fullStr Diarrhoea in Patients with COVID-19
title_full_unstemmed Diarrhoea in Patients with COVID-19
title_short Diarrhoea in Patients with COVID-19
title_sort diarrhoea in patients with covid 19
topic covid-19
diarrhoea
developmental mechanisms
url https://www.gastro-j.ru/jour/article/view/520
work_keys_str_mv AT aasheptulin diarrhoeainpatientswithcovid19