Autologous iPSC- and MSC-derived chondrocyte implants for cartilage repair in a miniature pig model

Autologous iPSC- and MSC-derived chondrocyte implants for cartilage repair in a miniature pig model

Abstract Background Induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSCs) have greater potential for generating chondrocytes without hypertrophic and fibrotic phenotypes compared to bone marrow-derived mesenchymal stem/stromal cells (BMSCs). However, there is a lack of research...

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Main Authors: Ming-Song Lee, Eric Chang-Yi Lin, Athillesh Sivapatham, Ellen M. Leiferman, Hongli Jiao, Yan Lu, Brett W. Nemke, Matthew Leiferman, Mark D. Markel, Wan-Ju Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-025-04215-7
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