Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature
In the first 90 days, most meningitis cases are viral. Newborns often show nonspecific symptoms, making early diagnosis difficult but crucial for effective treatment and good outcomes. Cerebro-spinal fluid (CSF) analysis is the gold standard for diagnosis, enabling targeted therapy. We report on a n...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/17/6/790 |
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| author | Carolina Coramusi Alessandra Rizzoli Caterina Alegiani Susanna Bonafoni Cinzia Auriti Pasquale Parisi Maria Eleonora Scapillati |
| author_facet | Carolina Coramusi Alessandra Rizzoli Caterina Alegiani Susanna Bonafoni Cinzia Auriti Pasquale Parisi Maria Eleonora Scapillati |
| author_sort | Carolina Coramusi |
| collection | DOAJ |
| description | In the first 90 days, most meningitis cases are viral. Newborns often show nonspecific symptoms, making early diagnosis difficult but crucial for effective treatment and good outcomes. Cerebro-spinal fluid (CSF) analysis is the gold standard for diagnosis, enabling targeted therapy. We report on a newborn with rare viral meningitis due to herpes simplex virus type 1 and enterovirus coinfection. This uncommon situation complicates diagnostic and therapeutic management. We share our experience and review the limited literature on such neonatal viral coinfections. |
| format | Article |
| id | doaj-art-5228098e244144e6a61f8efcbbb8d0d3 |
| institution | Kabale University |
| issn | 1999-4915 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-5228098e244144e6a61f8efcbbb8d0d32025-08-20T03:26:52ZengMDPI AGViruses1999-49152025-05-0117679010.3390/v17060790Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the LiteratureCarolina Coramusi0Alessandra Rizzoli1Caterina Alegiani2Susanna Bonafoni3Cinzia Auriti4Pasquale Parisi5Maria Eleonora Scapillati6Faculty of Medicine and Psychology, Sapienza University, 00185 Rome, ItalySan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, ItalySan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, ItalySan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, ItalyDepartmental Faculty of Medicine, Saint Camillus International University, 00131 Rome, ItalyNESMOS Department, Faculty of Medicine & Psychology, Sapienza University, c/o Sant’ Andrea Hospital, 00185 Rome, ItalySan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, ItalyIn the first 90 days, most meningitis cases are viral. Newborns often show nonspecific symptoms, making early diagnosis difficult but crucial for effective treatment and good outcomes. Cerebro-spinal fluid (CSF) analysis is the gold standard for diagnosis, enabling targeted therapy. We report on a newborn with rare viral meningitis due to herpes simplex virus type 1 and enterovirus coinfection. This uncommon situation complicates diagnostic and therapeutic management. We share our experience and review the limited literature on such neonatal viral coinfections.https://www.mdpi.com/1999-4915/17/6/790neonatal meningitisHSVenteroviruscoinfectionnewborncase report |
| spellingShingle | Carolina Coramusi Alessandra Rizzoli Caterina Alegiani Susanna Bonafoni Cinzia Auriti Pasquale Parisi Maria Eleonora Scapillati Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature Viruses neonatal meningitis HSV enterovirus coinfection newborn case report |
| title | Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature |
| title_full | Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature |
| title_fullStr | Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature |
| title_full_unstemmed | Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature |
| title_short | Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature |
| title_sort | neonatal meningitis due to herpes simplex virus type 1 and enterovirus coinfection case report and review of the literature |
| topic | neonatal meningitis HSV enterovirus coinfection newborn case report |
| url | https://www.mdpi.com/1999-4915/17/6/790 |
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