A Narrative Review of RAS Mutations in Early-Stage Colorectal Cancer: Mechanisms and Clinical Implications

A Narrative Review of RAS Mutations in Early-Stage Colorectal Cancer: Mechanisms and Clinical Implications

Colorectal cancer (CRC) is the third-most common cancer globally and a leading cause of cancer-related deaths. While the prognostic and predictive roles of RAS mutations in advanced CRC are well-established, their significance in early-stage CRC remains a topic of debate. Studies have been conducted...

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Bibliographic Details
Main Authors: Hasan Cagri Yildirim, Damla Gunenc, Elvina Almuradova, Osman Sutcuoglu, Suayib Yalcin
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Medicina
Subjects:
colon cancer
KRAS mutation
MSI/MSS status
prognostic markers
early-stage
survival
Online Access:https://www.mdpi.com/1648-9144/61/3/408
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