Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females

Autoimmune chronic active hepatitis (CAH) and primary sclerosing cholangitis (PSC) arc chronic diseases of the hepatobiliary system that have many clinical, immunologic and genetic features in common. Despite these similarities, there are few reports of the two diseases coexisting. Two young women w...

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Main Authors: Gerald Y. Minuk, Lloyd R. Sutherland, S. Chris Pappas, James K. Kelly, Sue E. Martin
Format: Article
Language:English
Published: Wiley 1988-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1988/218728
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author Gerald Y. Minuk
Lloyd R. Sutherland
S. Chris Pappas
James K. Kelly
Sue E. Martin
author_facet Gerald Y. Minuk
Lloyd R. Sutherland
S. Chris Pappas
James K. Kelly
Sue E. Martin
author_sort Gerald Y. Minuk
collection DOAJ
description Autoimmune chronic active hepatitis (CAH) and primary sclerosing cholangitis (PSC) arc chronic diseases of the hepatobiliary system that have many clinical, immunologic and genetic features in common. Despite these similarities, there are few reports of the two diseases coexisting. Two young women with clinical, biochemical, serologic, radiologic and histologic findings compatible with both autoimmune CAH and PSC are described. The observation that there may be a striking overlap in the features of these two diseases and recent improvements in diagnostic imaging of the biliary tract suggest that the association of these two diseases in the same individual may be more common than is presently appreciated.
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institution Kabale University
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language English
publishDate 1988-01-01
publisher Wiley
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series Canadian Journal of Gastroenterology
spelling doaj-art-5217583323b04b2eadf3f33986b2e2d42025-02-03T05:59:15ZengWileyCanadian Journal of Gastroenterology0835-79001988-01-0121222710.1155/1988/218728Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult FemalesGerald Y. Minuk0Lloyd R. Sutherland1S. Chris Pappas2James K. Kelly3Sue E. Martin4Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDepartment of Medicine, University of Calgary, Calgary, Alberta, CanadaLiver Disease Section, Digestive Diseases Branch NIADDK, National Institutes of Health, Bethesda, Maryland, USADepartment of Medicine, University of Calgary, Calgary, Alberta, CanadaLiver Disease Section, Digestive Diseases Branch NIADDK, National Institutes of Health, Bethesda, Maryland, USAAutoimmune chronic active hepatitis (CAH) and primary sclerosing cholangitis (PSC) arc chronic diseases of the hepatobiliary system that have many clinical, immunologic and genetic features in common. Despite these similarities, there are few reports of the two diseases coexisting. Two young women with clinical, biochemical, serologic, radiologic and histologic findings compatible with both autoimmune CAH and PSC are described. The observation that there may be a striking overlap in the features of these two diseases and recent improvements in diagnostic imaging of the biliary tract suggest that the association of these two diseases in the same individual may be more common than is presently appreciated.http://dx.doi.org/10.1155/1988/218728
spellingShingle Gerald Y. Minuk
Lloyd R. Sutherland
S. Chris Pappas
James K. Kelly
Sue E. Martin
Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
Canadian Journal of Gastroenterology
title Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
title_full Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
title_fullStr Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
title_full_unstemmed Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
title_short Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females
title_sort autoimmune chronic active hepatitis lupoid hepatitis and primary sclerosing cholangitis in two young adult females
url http://dx.doi.org/10.1155/1988/218728
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