Relevance of the GH-VEGFB/VEGFA axis in liver grafts from brain-dead donors with alcohol-associated liver disease

Relevance of the GH-VEGFB/VEGFA axis in liver grafts from brain-dead donors with alcohol-associated liver disease

IntroductionGrafts with alcohol-associated liver disease (ALD) subjected to prolonged cold ischaemia from donors after brain death (DBD) are typically unsuitable for transplantation. Here, we investigated the role of growth hormone (GH) in livers with ALD from DBDs and its relationship with vascular...

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Bibliographic Details
Main Authors: Marc Micó-Carnero, Carlos Rojano-Alfonso, Cristina Maroto-Serrat, Juan Carlos Cutrin, Araní Casillas-Ramírez, Carmen Peralta
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
liver transplantation
brain death
ALD
ischemia-reperfusion
growth hormone
VEGF
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1455258/full
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