Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia

In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999–2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002–2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes...

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Bibliographic Details
Main Authors: Alex-Mikael Barkoff, Tamara Kastrin, Katja Seme, Marta Grgič Vitek, Jussi Mertsola, Qiushui He
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2024-11-01
Series:Emerging Infectious Diseases
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Online Access:https://wwwnc.cdc.gov/eid/article/30/11/23-1393_article
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Summary:In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999–2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002–2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.
ISSN:1080-6040
1080-6059