Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles of Zidovudine in Rats

Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles of Zidovudine in Rats

Zidovudine-loaded solid lipid nanoparticles (AZT-SLNs) and zidovudine in solution were prepared and administered in rats. The aim of this research was to study whether the bioavailability of zidovudine can be improved by AZT-SLNs perorally to rats as compared to oral administration of zidovudine. Zi...

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Bibliographic Details
Main Authors:	Shah Purvin, Parameswara Rao Vuddanda, Sanjay Kumar Singh, Achint Jain, Sanjay Singh
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	Journal of Nanotechnology
Online Access:	http://dx.doi.org/10.1155/2014/854018
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