Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm

The coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host’s exagger...

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Main Authors: Jitendra Parmar, Tapan Patel, Sandip Shah, Jay Kothari, Sameer Dani, Sagar Vyas
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2021/6696443
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author Jitendra Parmar
Tapan Patel
Sandip Shah
Jay Kothari
Sameer Dani
Sagar Vyas
author_facet Jitendra Parmar
Tapan Patel
Sandip Shah
Jay Kothari
Sameer Dani
Sagar Vyas
author_sort Jitendra Parmar
collection DOAJ
description The coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host’s exaggerated inflammatory response representing cytokine dysregulation/storm which produces coagulopathy and vascular endothelial dysfunction, apart from a prothrombotic state. Cytokine storm or direct viral invasion of the vascular endothelial cells through surface angiotensin-converting enzyme 2 receptors may result in endothelial dysfunction which can potentially result in dissection. Only a few case reports have been published in the literature describing vascular dissection without any inciting factors in COVID-19 patients. Herein, we present the first case report of bilateral renal artery dissection in a 41-year-old male patient who recently recovered from COVID-19 and was managed successfully in stages after many medical hurdles.
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institution Kabale University
issn 2090-6420
2090-6439
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-5211216402ee4ddc8511c9241c896f742025-02-03T06:06:31ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/66964436696443Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine StormJitendra Parmar0Tapan Patel1Sandip Shah2Jay Kothari3Sameer Dani4Sagar Vyas5Department of Radiology, Apollo Hospitals International Limited, Ahmedabad, IndiaDepartment of Radiology, Apollo Hospitals International Limited, Ahmedabad, IndiaDepartment of Radiology, Apollo Hospitals International Limited, Ahmedabad, IndiaDepartment of Intensive and Critical Care, Apollo Hospitals International Limited, Ahmedabad, IndiaDepartment of Interventional Cardiology, Apollo Hospitals International Limited, Ahmedabad, IndiaDepartment of Intensive and Critical Care, Apollo Hospitals International Limited, Ahmedabad, IndiaThe coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host’s exaggerated inflammatory response representing cytokine dysregulation/storm which produces coagulopathy and vascular endothelial dysfunction, apart from a prothrombotic state. Cytokine storm or direct viral invasion of the vascular endothelial cells through surface angiotensin-converting enzyme 2 receptors may result in endothelial dysfunction which can potentially result in dissection. Only a few case reports have been published in the literature describing vascular dissection without any inciting factors in COVID-19 patients. Herein, we present the first case report of bilateral renal artery dissection in a 41-year-old male patient who recently recovered from COVID-19 and was managed successfully in stages after many medical hurdles.http://dx.doi.org/10.1155/2021/6696443
spellingShingle Jitendra Parmar
Tapan Patel
Sandip Shah
Jay Kothari
Sameer Dani
Sagar Vyas
Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
Case Reports in Critical Care
title Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
title_full Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
title_fullStr Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
title_full_unstemmed Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
title_short Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
title_sort spontaneous renal artery dissection in covid 19 pneumonia potential danger of cytokine storm
url http://dx.doi.org/10.1155/2021/6696443
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