Advanced Role of Neutrophils in Common Respiratory Diseases
Respiratory diseases, always being a threat towards the health of people all over the world, are most tightly associated with immune system. Neutrophils serve as an important component of immune defense barrier linking innate and adaptive immunity. They participate in the clearance of exogenous path...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/6710278 |
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| author | Jinping Liu Zhiqiang Pang Guoqiang Wang Xuewa Guan Keyong Fang Ziyan Wang Fang Wang |
| author_facet | Jinping Liu Zhiqiang Pang Guoqiang Wang Xuewa Guan Keyong Fang Ziyan Wang Fang Wang |
| author_sort | Jinping Liu |
| collection | DOAJ |
| description | Respiratory diseases, always being a threat towards the health of people all over the world, are most tightly associated with immune system. Neutrophils serve as an important component of immune defense barrier linking innate and adaptive immunity. They participate in the clearance of exogenous pathogens and endogenous cell debris and play an essential role in the pathogenesis of many respiratory diseases. However, the pathological mechanism of neutrophils remains complex and obscure. The traditional roles of neutrophils in severe asthma, chronic obstructive pulmonary diseases (COPD), pneumonia, lung cancer, pulmonary fibrosis, bronchitis, and bronchiolitis had already been reviewed. With the development of scientific research, the involvement of neutrophils in respiratory diseases is being brought to light with emerging data on neutrophil subsets, trafficking, and cell death mechanism (e.g., NETosis, apoptosis) in diseases. We reviewed all these recent studies here to provide you with the latest advances about the role of neutrophils in respiratory diseases. |
| format | Article |
| id | doaj-art-5204eb51d4a348079121f7793d3b99ae |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-5204eb51d4a348079121f7793d3b99ae2025-02-03T06:13:46ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/67102786710278Advanced Role of Neutrophils in Common Respiratory DiseasesJinping Liu0Zhiqiang Pang1Guoqiang Wang2Xuewa Guan3Keyong Fang4Ziyan Wang5Fang Wang6Institute of Frontier Medical Science, Jilin University, Changchun 130021, ChinaDepartment of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaRespiratory diseases, always being a threat towards the health of people all over the world, are most tightly associated with immune system. Neutrophils serve as an important component of immune defense barrier linking innate and adaptive immunity. They participate in the clearance of exogenous pathogens and endogenous cell debris and play an essential role in the pathogenesis of many respiratory diseases. However, the pathological mechanism of neutrophils remains complex and obscure. The traditional roles of neutrophils in severe asthma, chronic obstructive pulmonary diseases (COPD), pneumonia, lung cancer, pulmonary fibrosis, bronchitis, and bronchiolitis had already been reviewed. With the development of scientific research, the involvement of neutrophils in respiratory diseases is being brought to light with emerging data on neutrophil subsets, trafficking, and cell death mechanism (e.g., NETosis, apoptosis) in diseases. We reviewed all these recent studies here to provide you with the latest advances about the role of neutrophils in respiratory diseases.http://dx.doi.org/10.1155/2017/6710278 |
| spellingShingle | Jinping Liu Zhiqiang Pang Guoqiang Wang Xuewa Guan Keyong Fang Ziyan Wang Fang Wang Advanced Role of Neutrophils in Common Respiratory Diseases Journal of Immunology Research |
| title | Advanced Role of Neutrophils in Common Respiratory Diseases |
| title_full | Advanced Role of Neutrophils in Common Respiratory Diseases |
| title_fullStr | Advanced Role of Neutrophils in Common Respiratory Diseases |
| title_full_unstemmed | Advanced Role of Neutrophils in Common Respiratory Diseases |
| title_short | Advanced Role of Neutrophils in Common Respiratory Diseases |
| title_sort | advanced role of neutrophils in common respiratory diseases |
| url | http://dx.doi.org/10.1155/2017/6710278 |
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