Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women

Background and objectives. The elderly population is growing rapidly. The aging process will result in the decline of cognitive functions. The frequency of cognitive impairment is higher in women than in men, resulting in a greater risk of decreased quality of life and dependence. Brain-derived neur...

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Main Authors: Nadia Rizki Rahmawati, Damayanti Tinduh, Ditaruni Asrina Utami, Budi Utomo
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2024-06-01
Series:Romanian Journal of Neurology
Subjects:
Online Access:https://rjn.com.ro/articles/2024.2/RJN_2024_2_Art-11.pdf
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author Nadia Rizki Rahmawati
Damayanti Tinduh
Ditaruni Asrina Utami
Budi Utomo
author_facet Nadia Rizki Rahmawati
Damayanti Tinduh
Ditaruni Asrina Utami
Budi Utomo
author_sort Nadia Rizki Rahmawati
collection DOAJ
description Background and objectives. The elderly population is growing rapidly. The aging process will result in the decline of cognitive functions. The frequency of cognitive impairment is higher in women than in men, resulting in a greater risk of decreased quality of life and dependence. Brain-derived neurotrophic growth factor (BDNF) is part of neurotrophins that play a key role in the cognitive process. Physical exercise can improve cognitive function in the normal aging process by triggering increased expression of neurotrophic factors such as BDNF, one type of which is exergame boxing. This study aims to analyze the effect of the exergame boxing addition on the brain-derived neurotrophic factor of elderly women. Materials and methods. The study subjects were 30 elderly women, divided into treatment and control groups. Participants in the treatment group practiced exergame boxing three times per week for eight weeks. Participants in both groups were required to participate in light intensity aerobic exercise five times a week for ±15 minutes. Serum BDNF levels were assessed before and after eight weeks of exercise. Results. There was a significant increase in serum BDNF levels after the addition of exergame boxing for eight weeks in the treatment group (p = 0.002) with an effect size of 0,62. There was no significant increase in serum BDNF levels after eight weeks of light intensity aerobic exercise in the control group (p-value = 0.480). There was a significant difference in the treatment group who received the addition of exergame boxing training for eight weeks compared to the control group who only received light intensity aerobic exercise (p = 0.038). Conclusion. The addition of boxing exergame to light intensity aerobic exercise for eight weeks can improve the BDNF serum of elderly women compared to the use of light intensity aerobic exercise alone.
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2069-6094
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spelling doaj-art-5201b4fe1489443597dc30261124a9f02025-08-20T01:59:14ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942024-06-0123215415910.37897/RJN.2024.2.11Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly womenNadia Rizki Rahmawati0https://orcid.org/0009-0006-0482-325XDamayanti Tinduh1https://orcid.org/0000-0001-6604-8152Ditaruni Asrina Utami2Budi Utomo3Faculty of Medicine Airlangga University, Surabaya, Indonesia; Department of Physical Medicine and Rehabilitation, “Dr. Soetomo” General Academic Hospital, Surabaya, IndonesiaFaculty of Medicine Airlangga University, Surabaya, Indonesia; Sport Injury Rehabilitation Division, Department of Physical Medicine and Rehabilitation, “Dr. Soetomo” General Academic Hospital, Surabaya, IndonesiaFaculty of Medicine Airlangga University, Surabaya, Indonesia; Musculoskeletal Rehabilitation Division, Department of Physical Medicine and Rehabilitation, Airlangga University Hospital, Surabaya, IndonesiaDepartment of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, Universitas Airlangga, Surabaya, IndonesiaBackground and objectives. The elderly population is growing rapidly. The aging process will result in the decline of cognitive functions. The frequency of cognitive impairment is higher in women than in men, resulting in a greater risk of decreased quality of life and dependence. Brain-derived neurotrophic growth factor (BDNF) is part of neurotrophins that play a key role in the cognitive process. Physical exercise can improve cognitive function in the normal aging process by triggering increased expression of neurotrophic factors such as BDNF, one type of which is exergame boxing. This study aims to analyze the effect of the exergame boxing addition on the brain-derived neurotrophic factor of elderly women. Materials and methods. The study subjects were 30 elderly women, divided into treatment and control groups. Participants in the treatment group practiced exergame boxing three times per week for eight weeks. Participants in both groups were required to participate in light intensity aerobic exercise five times a week for ±15 minutes. Serum BDNF levels were assessed before and after eight weeks of exercise. Results. There was a significant increase in serum BDNF levels after the addition of exergame boxing for eight weeks in the treatment group (p = 0.002) with an effect size of 0,62. There was no significant increase in serum BDNF levels after eight weeks of light intensity aerobic exercise in the control group (p-value = 0.480). There was a significant difference in the treatment group who received the addition of exergame boxing training for eight weeks compared to the control group who only received light intensity aerobic exercise (p = 0.038). Conclusion. The addition of boxing exergame to light intensity aerobic exercise for eight weeks can improve the BDNF serum of elderly women compared to the use of light intensity aerobic exercise alone.https://rjn.com.ro/articles/2024.2/RJN_2024_2_Art-11.pdfelderly womenexergame boxingcognitivebrain-derived neurotrophic growth factorbdnf
spellingShingle Nadia Rizki Rahmawati
Damayanti Tinduh
Ditaruni Asrina Utami
Budi Utomo
Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
Romanian Journal of Neurology
elderly women
exergame boxing
cognitive
brain-derived neurotrophic growth factor
bdnf
title Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
title_full Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
title_fullStr Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
title_full_unstemmed Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
title_short Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women
title_sort effect of boxing exergame addition on brain derived neurotrophic factor of elderly women
topic elderly women
exergame boxing
cognitive
brain-derived neurotrophic growth factor
bdnf
url https://rjn.com.ro/articles/2024.2/RJN_2024_2_Art-11.pdf
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AT ditaruniasrinautami effectofboxingexergameadditiononbrainderivedneurotrophicfactorofelderlywomen
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