Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City
Background and objectives:Hepatitis-B virus is one of the most serious and prevalent health problems. Vaccination against Hepatitis-B virus is the most effective way of preventing infection and transmission of the virus. The aim of this study was to assess the effectiveness of hepatitis-B virus vac...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2023-04-01
|
| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/172 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850201539709239296 |
|---|---|
| author | Razhan Sabah Hassan Ali Hattem Bayati |
| author_facet | Razhan Sabah Hassan Ali Hattem Bayati |
| author_sort | Razhan Sabah Hassan |
| collection | DOAJ |
| description |
Background and objectives:Hepatitis-B virus is one of the most serious and prevalent health problems. Vaccination against Hepatitis-B virus is the most effective way of preventing infection and transmission of the virus. The aim of this study was to assess the effectiveness of hepatitis-B virus vaccination among children in Sulaimani city
Methods: A cross-sectional study was performed on 384 children aged between 1 and 14 years who received the scheduled 3 doses of hepatitis B virus vaccine in infancy period. Blood samples were taken from all children, and the sera were tested for antibody to hepatitis B surface antigen, antibody to hepatitis B core antigen, and hepatitis B surface antigen using enzyme-linked immunosorbent assay
Results: Hepatitis B surface antigen and total antibody to hepatitis B core antigen were negative in all children involved in the study whereas antibody to hepatitis B surface antigen was positive (antibody to hepatitis B surface antigen ? 10 mIU/mL) in 256 (66.7%) and negative (antibody to hepatitis B surface antigen < 10 mIU/mL) in 128 (33.3%) children; (77.3%) of children in the age group 1-5 years were positive for antibody to hepatitis B surface antigen, while the percentage was less (66.7%) in the age group 6-10 years and least (57.9%) in the age group 11-14 years, these differences in the age groups were statistically significant, p value <0.02.
Conclusions: Universal Hepatitis B virus vaccination program provided protection to nearly two thirds of children in Sulaimani city, Kurdistan Region, Iraq, and seronegative antibody to hepatitis B surface antigen exists in different age groups of the vaccinated children.
|
| format | Article |
| id | doaj-art-51feddc12a0e4985baab7668191e55de |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-51feddc12a0e4985baab7668191e55de2025-08-20T02:11:58ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802023-04-014210.56056/amj.2018.63173Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani CityRazhan Sabah Hassan0Ali Hattem Bayati1Postgraduate student, Microbiology/Pathology, Kurdistan Board of Medical Specialties/ Kurdistan region-Iraq. Assistant Professor, Community Health Department, Technical College of Health, Sulaimani Polytechnic University, Sulaimani City, Kurdistan Region-Iraq. Background and objectives:Hepatitis-B virus is one of the most serious and prevalent health problems. Vaccination against Hepatitis-B virus is the most effective way of preventing infection and transmission of the virus. The aim of this study was to assess the effectiveness of hepatitis-B virus vaccination among children in Sulaimani city Methods: A cross-sectional study was performed on 384 children aged between 1 and 14 years who received the scheduled 3 doses of hepatitis B virus vaccine in infancy period. Blood samples were taken from all children, and the sera were tested for antibody to hepatitis B surface antigen, antibody to hepatitis B core antigen, and hepatitis B surface antigen using enzyme-linked immunosorbent assay Results: Hepatitis B surface antigen and total antibody to hepatitis B core antigen were negative in all children involved in the study whereas antibody to hepatitis B surface antigen was positive (antibody to hepatitis B surface antigen ? 10 mIU/mL) in 256 (66.7%) and negative (antibody to hepatitis B surface antigen < 10 mIU/mL) in 128 (33.3%) children; (77.3%) of children in the age group 1-5 years were positive for antibody to hepatitis B surface antigen, while the percentage was less (66.7%) in the age group 6-10 years and least (57.9%) in the age group 11-14 years, these differences in the age groups were statistically significant, p value <0.02. Conclusions: Universal Hepatitis B virus vaccination program provided protection to nearly two thirds of children in Sulaimani city, Kurdistan Region, Iraq, and seronegative antibody to hepatitis B surface antigen exists in different age groups of the vaccinated children. https://amj.khcms.edu.krd/index.php/main/article/view/172Antibody to hepatitis B surface antigenHepatitis B virusVaccinationSulaimani City |
| spellingShingle | Razhan Sabah Hassan Ali Hattem Bayati Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City Advanced Medical Journal Antibody to hepatitis B surface antigen Hepatitis B virus Vaccination Sulaimani City |
| title | Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City |
| title_full | Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City |
| title_fullStr | Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City |
| title_full_unstemmed | Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City |
| title_short | Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City |
| title_sort | evaluation of the effectiveness of hepatitis b vaccination in children aged 1 to 14 years in sulaimani city |
| topic | Antibody to hepatitis B surface antigen Hepatitis B virus Vaccination Sulaimani City |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/172 |
| work_keys_str_mv | AT razhansabahhassan evaluationoftheeffectivenessofhepatitisbvaccinationinchildrenaged1to14yearsinsulaimanicity AT alihattembayati evaluationoftheeffectivenessofhepatitisbvaccinationinchildrenaged1to14yearsinsulaimanicity |