Evaluation of the Effectiveness of Hepatitis B Vaccination in Children Aged 1 to 14 Years in Sulaimani City
Background and objectives:Hepatitis-B virus is one of the most serious and prevalent health problems. Vaccination against Hepatitis-B virus is the most effective way of preventing infection and transmission of the virus. The aim of this study was to assess the effectiveness of hepatitis-B virus vac...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2023-04-01
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| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/172 |
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| Summary: | Background and objectives:Hepatitis-B virus is one of the most serious and prevalent health problems. Vaccination against Hepatitis-B virus is the most effective way of preventing infection and transmission of the virus. The aim of this study was to assess the effectiveness of hepatitis-B virus vaccination among children in Sulaimani city
Methods: A cross-sectional study was performed on 384 children aged between 1 and 14 years who received the scheduled 3 doses of hepatitis B virus vaccine in infancy period. Blood samples were taken from all children, and the sera were tested for antibody to hepatitis B surface antigen, antibody to hepatitis B core antigen, and hepatitis B surface antigen using enzyme-linked immunosorbent assay
Results: Hepatitis B surface antigen and total antibody to hepatitis B core antigen were negative in all children involved in the study whereas antibody to hepatitis B surface antigen was positive (antibody to hepatitis B surface antigen ? 10 mIU/mL) in 256 (66.7%) and negative (antibody to hepatitis B surface antigen < 10 mIU/mL) in 128 (33.3%) children; (77.3%) of children in the age group 1-5 years were positive for antibody to hepatitis B surface antigen, while the percentage was less (66.7%) in the age group 6-10 years and least (57.9%) in the age group 11-14 years, these differences in the age groups were statistically significant, p value <0.02.
Conclusions: Universal Hepatitis B virus vaccination program provided protection to nearly two thirds of children in Sulaimani city, Kurdistan Region, Iraq, and seronegative antibody to hepatitis B surface antigen exists in different age groups of the vaccinated children.
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| ISSN: | 2958-8979 2957-3580 |