The Use of Intrinsic Disorder and Phosphorylation by Oncogenic Viral Proteins to Dysregulate the Host Cell Cycle Through Interaction with pRb

The Use of Intrinsic Disorder and Phosphorylation by Oncogenic Viral Proteins to Dysregulate the Host Cell Cycle Through Interaction with pRb

Approximately 15% of cancers worldwide are caused by oncogenic viruses. These infectious agents utilize multiple strategies to dysregulate their host cells as a means of viral reproduction. While this typically involves a small number of viral oncoproteins known to interact with a myriad of host cel...

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Bibliographic Details
Main Authors: Heidi Kast-Woelbern, Sarah K. Martinho, Kayla T. Julio, Audrey M. Vazzana, Abbey E. Mandagie, Ariane L. Jansma
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Viruses
Subjects:
oncogenic virus
intrinsically disordered protein
phosphorylation
Online Access:https://www.mdpi.com/1999-4915/17/6/835
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