Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR–a randomised controlled trialResearch in context

Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR–a randomised controlled trialResearch in context

Summary: Background: Children born extremely preterm are at increased risk of developmental problems and respiratory morbidity due to patent ductus arteriosus (PDA). The objective of this study was to evaluate whether early treatment of a PDA ≥1.5 mm with ibuprofen improved neurodevelopmental and r...

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Main Authors: Samir Gupta, Heather O'Connor, Edmund Juszczak, Nimish V. Subhedar, Ursula Bowler, Charlotte Clarke, David Field, Elizabeth Hutchison, Wilf Kelsall, Justine Pepperell, Tracy Roberts, Sunil Sinha, Kayleigh Stanbury, Jonathan Wyllie, Pollyanna Hardy, Samantha Johnson
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:EClinicalMedicine
Subjects:
Patent ductus arteriosus
Premature
Neurodevelopmental outcomes
Respiratory outcome
Death
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537025003566
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