Clinical and Economic Outcomes of Intradiscal Injection of Condoliase for a Treatment of Lumbar Disc Herniation with Severe Low Back Pain: A Multicenter Study

Clinical and Economic Outcomes of Intradiscal Injection of Condoliase for a Treatment of Lumbar Disc Herniation with Severe Low Back Pain: A Multicenter Study

Introduction: Chemonucleolysis with condoliase (chondroitin sulfate ABC endolyase) has been widely employed to treat patients with lumbar disc herniation (LDH) in Japan. Although it is an effective and relatively safe treatment for radicular neuropathy in patients with LDH, there have been no report...

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Main Authors: Takashi Hirai, Takuya Takahashi, Yohei Takahashi, Kota Watanabe, Tomohiro Banno, Kyohei Sakaki, Yoshiyasu Arai, Yuichi Takano, Yawara Eguchi, Yuki Taniguchi, Satoshi Maki, Yasuchika Aoki, Shunichi Fujii, Kentaro Sakaeda, Yu Matsukura, Tsutomu Akazawa, Akihito Minamide, Hidetoshi Nojiri, Kenichiro Sakai, Satoshi Kato, Koji Tamai, Hidekazu Suzuki, Masayuki Miyagi, Hiroyuki Sato, Toshitaka Yoshii, Hiroshi Yamada, Takashi Kaito, Yutaka Hiraizumi, Masatsune Yamagata, Masaya Nakamura, Akihiro Hirakawa, Naofumi Hosogane, Seiji Ohtori
Format: Article
Language:English
Published: The Japanese Society for Spine Surgery and Related Research 2025-05-01
Series:Spine Surgery and Related Research
Subjects:
intradiscal injection
condoliase
chemonucleolysis
lumbar intervertebral disc herniation
radiculopathy
leg pain
low back pain
medical cost
Online Access:https://www.jstage.jst.go.jp/article/ssrr/9/3/9_2024-0288/_pdf/-char/en
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