Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i>
Lead (Pb) is a non-essential toxic metal that accumulates in aquatic environments, negatively impacting fish health. This study evaluated the acute toxicity of Pb in starry flounders (<i>Platichthys stellatus</i>). Fish (41 ± 8.1 g, 14 ± 0.9 cm) were exposed to Pb concentrations of 0, 10...
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MDPI AG
2025-03-01
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| author | Min-Jung Kim Kyung Mi Lee Sung-Pyo Hur Cheol Young Choi Jun-Hwan Kim |
| author_facet | Min-Jung Kim Kyung Mi Lee Sung-Pyo Hur Cheol Young Choi Jun-Hwan Kim |
| author_sort | Min-Jung Kim |
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| description | Lead (Pb) is a non-essential toxic metal that accumulates in aquatic environments, negatively impacting fish health. This study evaluated the acute toxicity of Pb in starry flounders (<i>Platichthys stellatus</i>). Fish (41 ± 8.1 g, 14 ± 0.9 cm) were exposed to Pb concentrations of 0, 10, 20, 40, 80, 160, 320, and 640 mg Pb<sup>2+</sup>/L for 96 h. The lethal concentration (96 h LC<sub>50</sub>) was determined to be 227 mg Pb<sup>2+</sup>/L. Hematological analysis showed significant decreases in RBC counts, hemoglobin, and hematocrit, while MCH and MCHC increased at ≥160 mg Pb<sup>2+</sup>/L. Plasma calcium levels significantly decreased following Pb exposure, and AST activity was reduced. These findings suggest that acute waterborne Pb exposure adversely affects survival, hematological parameters, and plasma components in <i>P. stellatus</i>, providing insight into Pb toxicity in aquatic organisms. |
| format | Article |
| id | doaj-art-51ecc7d410c74643be2fbb6e911217c0 |
| institution | DOAJ |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
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| spelling | doaj-art-51ecc7d410c74643be2fbb6e911217c02025-08-20T03:08:43ZengMDPI AGAnimals2076-26152025-03-0115793210.3390/ani15070932Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i>Min-Jung Kim0Kyung Mi Lee1Sung-Pyo Hur2Cheol Young Choi3Jun-Hwan Kim4Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of KoreaAquaculture Industry Division, West Sea Fisheries Research Institute, National Institute of Fisheries Science, Incheon 22383, Republic of KoreaDepartment of Marine Life Science, Jeju National University, Jeju 63243, Republic of KoreaDivision of Marine BioScience, National Korea Maritime and Ocean University, Busan 49112, Republic of KoreaDepartment of Marine Life Science, Jeju National University, Jeju 63243, Republic of KoreaLead (Pb) is a non-essential toxic metal that accumulates in aquatic environments, negatively impacting fish health. This study evaluated the acute toxicity of Pb in starry flounders (<i>Platichthys stellatus</i>). Fish (41 ± 8.1 g, 14 ± 0.9 cm) were exposed to Pb concentrations of 0, 10, 20, 40, 80, 160, 320, and 640 mg Pb<sup>2+</sup>/L for 96 h. The lethal concentration (96 h LC<sub>50</sub>) was determined to be 227 mg Pb<sup>2+</sup>/L. Hematological analysis showed significant decreases in RBC counts, hemoglobin, and hematocrit, while MCH and MCHC increased at ≥160 mg Pb<sup>2+</sup>/L. Plasma calcium levels significantly decreased following Pb exposure, and AST activity was reduced. These findings suggest that acute waterborne Pb exposure adversely affects survival, hematological parameters, and plasma components in <i>P. stellatus</i>, providing insight into Pb toxicity in aquatic organisms.https://www.mdpi.com/2076-2615/15/7/932Pb exposureLC<sub>50</sub>hematological parametersplasma componentsstarry flounder |
| spellingShingle | Min-Jung Kim Kyung Mi Lee Sung-Pyo Hur Cheol Young Choi Jun-Hwan Kim Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> Animals Pb exposure LC<sub>50</sub> hematological parameters plasma components starry flounder |
| title | Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> |
| title_full | Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> |
| title_fullStr | Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> |
| title_full_unstemmed | Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> |
| title_short | Toxic Effects of Waterborne Pb Exposure on Hematological Parameters and Plasma Components in Starry Flounder, <i>Platichthys stellatus</i> |
| title_sort | toxic effects of waterborne pb exposure on hematological parameters and plasma components in starry flounder i platichthys stellatus i |
| topic | Pb exposure LC<sub>50</sub> hematological parameters plasma components starry flounder |
| url | https://www.mdpi.com/2076-2615/15/7/932 |
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