Proinflammatory follicular helper T cells promote immunoglobulin G secretion, suppress regulatory B cell development, and correlate with worse clinical outcomes in gastric cancer

Proinflammatory follicular helper T cells promote immunoglobulin G secretion, suppress regulatory B cell development, and correlate with worse clinical outcomes in gastric cancer

Gastric cancer is one of the most common and aggressive malignancies. Both bacterial virulence factors and host chronic inflammation are thought to promote gastric cancer development. In this study, we investigated the potential involvement of follicular helper T cells in gastric cancer. Functions o...

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Main Authors: Hong Zhang, Rongxi Yue, Pengfei Zhao, Xuetao Yu, Junguo Li, Guoqing Ma, Jiahong Tang, Lixin Zhang, Liying Feng, Lidong Sun, Zongchang Song, Chunliang Guo, Ning Wang
Format: Article
Language:English
Published: SAGE Publishing 2017-05-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705747
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