Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA
Mineral elements are essential for human health. Our previous study identified distinct clusters of health-related mineral elements in surface soil among different regions and demonstrated an association between these clusters and health profiles in the USA. The present study further explores the re...
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MDPI AG
2025-05-01
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| author | Bingjie Qu Qiaochu Xu Linxi Yuan Ying Chen |
| author_facet | Bingjie Qu Qiaochu Xu Linxi Yuan Ying Chen |
| author_sort | Bingjie Qu |
| collection | DOAJ |
| description | Mineral elements are essential for human health. Our previous study identified distinct clusters of health-related mineral elements in surface soil among different regions and demonstrated an association between these clusters and health profiles in the USA. The present study further explores the relationship between these mineral clusters and mortality from detailed specific types of cancers and cardiovascular diseases by using county-level data from 3080 counties across the USA. Utilizing multivariate regression models with adjustment for socio-demographic and geographical factors, our analysis of county-level data revealed that residents in the regions of ‘infertile’ cluster have higher mortality rates for most types of cancers (18/29) and cardiovascular conditions (4/10) compared with people who live elsewhere. Notably, this relationship is pronounced for several specific leading causes of death such as tracheal, bronchus, lung cancer (regression coefficient (99.5% CIs), 6.29 (4.46, 8.13)), prostate cancer (1.06 (0.53, 1.6)), cerebrovascular disease (3.15 (1.74, 4.55)), and hypertensive heart disease (1.23 (0.23, 2.23)). Our findings highlight the critical role of soil minerals in human health and underscore the need for integrating geochemical data in public health strategies and environmental management policies. |
| format | Article |
| id | doaj-art-51e6b52ad13b47d0ad461b65263ceb68 |
| institution | OA Journals |
| issn | 2075-1729 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
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| series | Life |
| spelling | doaj-art-51e6b52ad13b47d0ad461b65263ceb682025-08-20T02:21:03ZengMDPI AGLife2075-17292025-05-0115683210.3390/life15060832Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USABingjie Qu0Qiaochu Xu1Linxi Yuan2Ying Chen3Wisdom Lake Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, Suzhou 215123, ChinaWisdom Lake Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, Suzhou 215123, ChinaDepartment of Health and Environmental Sciences, Xi’an Jiaotong-Liverpool University, Suzhou 215123, ChinaWisdom Lake Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, Suzhou 215123, ChinaMineral elements are essential for human health. Our previous study identified distinct clusters of health-related mineral elements in surface soil among different regions and demonstrated an association between these clusters and health profiles in the USA. The present study further explores the relationship between these mineral clusters and mortality from detailed specific types of cancers and cardiovascular diseases by using county-level data from 3080 counties across the USA. Utilizing multivariate regression models with adjustment for socio-demographic and geographical factors, our analysis of county-level data revealed that residents in the regions of ‘infertile’ cluster have higher mortality rates for most types of cancers (18/29) and cardiovascular conditions (4/10) compared with people who live elsewhere. Notably, this relationship is pronounced for several specific leading causes of death such as tracheal, bronchus, lung cancer (regression coefficient (99.5% CIs), 6.29 (4.46, 8.13)), prostate cancer (1.06 (0.53, 1.6)), cerebrovascular disease (3.15 (1.74, 4.55)), and hypertensive heart disease (1.23 (0.23, 2.23)). Our findings highlight the critical role of soil minerals in human health and underscore the need for integrating geochemical data in public health strategies and environmental management policies.https://www.mdpi.com/2075-1729/15/6/832soil mineralgeochemistrygeochemical patterncause-specific deathcancercardiovascular condition |
| spellingShingle | Bingjie Qu Qiaochu Xu Linxi Yuan Ying Chen Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA Life soil mineral geochemistry geochemical pattern cause-specific death cancer cardiovascular condition |
| title | Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA |
| title_full | Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA |
| title_fullStr | Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA |
| title_full_unstemmed | Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA |
| title_short | Association Between Soil Patterns and Mortality with Distinct Types of Cancers and CVD Across the USA |
| title_sort | association between soil patterns and mortality with distinct types of cancers and cvd across the usa |
| topic | soil mineral geochemistry geochemical pattern cause-specific death cancer cardiovascular condition |
| url | https://www.mdpi.com/2075-1729/15/6/832 |
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