Conserved function of bat TBK1 in activating innate immunity against RNA viruses: insights into the innate immune response in bats

Conserved function of bat TBK1 in activating innate immunity against RNA viruses: insights into the innate immune response in bats

Bats exhibit unique abilities to coexist with viruses asymptomatically, setting them apart among mammals. The innate immune system serves as the primary defense against pathogens. As a crucial central node protein in this system, TANK binding kinase 1(TBK1) can receive signals from multiple pattern...

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Bibliographic Details
Main Authors: Qiuju Liu, Qi Shao, Caixia Xu, Chao Liu, Shuhan Li, Jie Wang, Xia Liu, Kehui Zhang, Yaxian Yan, Jianhe Sun, Yuqiang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
BAT
TBK1
virus
innate immunity
IFNβ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574866/full
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