Construction of a myocardial and skeletal muscle-specific Cyr61 gene knockout mouse model
Objective To construct a conditional knockout mice model of cysteine-rich angiogenesis inducer 61 (Cyr61, also known as Ccn1) gene in myocardium and skeletal muscle regulated by CRE recombinant enzyme. Methods C57BL/6 mice were used to create CKmm-Cre+/- Cyr61flox/flox mice by using CRISPR/Cas9 tech...
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| Main Author: | |
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| Format: | Article |
| Language: | zho |
| Published: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2025-06-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-6-720.pdf |
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