Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure
Background: A patent foramen ovale (PFO) has a complex anatomy, and evaluating the size before closure may be challenging. We aimed to investigate the correlation between preprocedural transesophageal echocardiography (TEE) and balloon sizing of PFO in patients undergoing percutaneous PFO closure. M...
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Elsevier
2025-01-01
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| Series: | Structural Heart |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2474870624001362 |
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| author | Birgitte Carbuhn Larsen, MD Martin Christian Harmsen, MD Henrik Vase, MD, PhD Jens Erik Nielsen-Kudsk, MD, DMSc Asger Andersen, MD, PhD |
| author_facet | Birgitte Carbuhn Larsen, MD Martin Christian Harmsen, MD Henrik Vase, MD, PhD Jens Erik Nielsen-Kudsk, MD, DMSc Asger Andersen, MD, PhD |
| author_sort | Birgitte Carbuhn Larsen, MD |
| collection | DOAJ |
| description | Background: A patent foramen ovale (PFO) has a complex anatomy, and evaluating the size before closure may be challenging. We aimed to investigate the correlation between preprocedural transesophageal echocardiography (TEE) and balloon sizing of PFO in patients undergoing percutaneous PFO closure. Methods: A retrospective single-center study with analysis of 100 patients who, due to paradox thromboembolism in the left circulation, underwent percutaneous PFO closure. The PFO sizing was compared to measures attained by TEE and balloon sizing using linear regression analysis. Results: PFO size measured by TEE occurred smaller than balloon sizing (2.19 mm [95% CI: 1.91 to 2.46] vs. 8.51 mm [95% CI: 8.02 to 9.00], p < 0.001). Additionally, neither the PFO channel length nor the atrial septal mobility measured by TEE correlated to the PFO size attained by balloon sizing, respectively (slope −0.018 [95% CI: −0.117 to 0.081], R = 0.036, p = 0.719) and (slope 0.049 [95% CI: ?0.043 to 0.141], R = 0.105, p = 0.297). Statistically significant difference in regression analysis but poor correlation was found between both TEE attained PFO and shunt size when compared to balloon sizing. Diverting patients according to the size of the PFO shunt was not statistically significant between PFO of moderate size compared, respectively, to a large and small PFO size. However, a difference was observed between a small and large PFO shunt size. Conclusions: PFO defect and shunt size measured by TEE showed a poor correlation with balloon sizing. Neither PFO channel length nor septal mobility were correlated to the PFO size measured by balloon sizing. |
| format | Article |
| id | doaj-art-51c9ca9e8b154648995a8685603f40fb |
| institution | Kabale University |
| issn | 2474-8706 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Structural Heart |
| spelling | doaj-art-51c9ca9e8b154648995a8685603f40fb2025-02-10T04:34:42ZengElsevierStructural Heart2474-87062025-01-0191100375Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous ClosureBirgitte Carbuhn Larsen, MD0Martin Christian Harmsen, MD1Henrik Vase, MD, PhD2Jens Erik Nielsen-Kudsk, MD, DMSc3Asger Andersen, MD, PhD4Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Internal Medicine, Regional Hospital Randers, Randers, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Address correspondence to: Asger Andersen, MD, PhD, Department of Cardiology, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, Aarhus N DK-8200.Background: A patent foramen ovale (PFO) has a complex anatomy, and evaluating the size before closure may be challenging. We aimed to investigate the correlation between preprocedural transesophageal echocardiography (TEE) and balloon sizing of PFO in patients undergoing percutaneous PFO closure. Methods: A retrospective single-center study with analysis of 100 patients who, due to paradox thromboembolism in the left circulation, underwent percutaneous PFO closure. The PFO sizing was compared to measures attained by TEE and balloon sizing using linear regression analysis. Results: PFO size measured by TEE occurred smaller than balloon sizing (2.19 mm [95% CI: 1.91 to 2.46] vs. 8.51 mm [95% CI: 8.02 to 9.00], p < 0.001). Additionally, neither the PFO channel length nor the atrial septal mobility measured by TEE correlated to the PFO size attained by balloon sizing, respectively (slope −0.018 [95% CI: −0.117 to 0.081], R = 0.036, p = 0.719) and (slope 0.049 [95% CI: ?0.043 to 0.141], R = 0.105, p = 0.297). Statistically significant difference in regression analysis but poor correlation was found between both TEE attained PFO and shunt size when compared to balloon sizing. Diverting patients according to the size of the PFO shunt was not statistically significant between PFO of moderate size compared, respectively, to a large and small PFO size. However, a difference was observed between a small and large PFO shunt size. Conclusions: PFO defect and shunt size measured by TEE showed a poor correlation with balloon sizing. Neither PFO channel length nor septal mobility were correlated to the PFO size measured by balloon sizing.http://www.sciencedirect.com/science/article/pii/S2474870624001362Balloon sizingPatent foramen ovalePercutaneous patent foramen ovale closureTransesophageal echocardiography |
| spellingShingle | Birgitte Carbuhn Larsen, MD Martin Christian Harmsen, MD Henrik Vase, MD, PhD Jens Erik Nielsen-Kudsk, MD, DMSc Asger Andersen, MD, PhD Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure Structural Heart Balloon sizing Patent foramen ovale Percutaneous patent foramen ovale closure Transesophageal echocardiography |
| title | Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure |
| title_full | Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure |
| title_fullStr | Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure |
| title_full_unstemmed | Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure |
| title_short | Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure |
| title_sort | comparison of patent foramen ovale sizing by transesophageal echocardiography and balloon sizing in patients undergoing percutaneous closure |
| topic | Balloon sizing Patent foramen ovale Percutaneous patent foramen ovale closure Transesophageal echocardiography |
| url | http://www.sciencedirect.com/science/article/pii/S2474870624001362 |
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