L-arginine regulates mitochondrial function and oxidative stress in the acute kidney injury model of unilateral ureter obstruction

L-arginine regulates mitochondrial function and oxidative stress in the acute kidney injury model of unilateral ureter obstruction

Acute kidney injury (AKI) is a significant clinical problem associated with high morbidity and mortality. Unilateral ureter obstruction (UUO) is a well-established model for studying the pathophysiology of AKI. L arginine (ARG), a precursor of nitric oxide, has been shown to possess renoprotective p...

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Bibliographic Details
Main Authors: Seyed Mohammad Amin Kashani, Narges Abdoli, Forouzan Khodaei, Zahra Honarpishefard, Tahereh Golzar, Nazi Dastkhosh, Azad Salimi, Negar Azarpira, Hossein Niknahad, Reza Heidari
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-03-01
Series:Trends in Pharmaceutical Sciences
Subjects:
acute kidney injury
mitochondrial impairment
nephrotoxicity
renal failure
Online Access:https://tips.sums.ac.ir/article_50844_dc44a8970cdc6a1c839bc26fb0a0f3b2.pdf
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